AP3S1

Gene Symbol AP3S1
Entrez Gene 1176
Alt Symbol CLAPS3, Sigma3A
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 3, sigma 1 subunit
Other Description AP-3 complex sigma-3A subunit|AP-3 complex subunit sigma-1|AP-3 complex subunit sigma-3A|adapter-related protein complex 3 sigma-1 subunit|adapter-related protein complex 3 subunit sigma-1|adaptor-related protein complex 3 subunit sigma-1|clathrin-associated/assembly/adapter protein, small 3|clathrin-associated/assembly/adaptor protein, small 3 (22kD)|sigma-3A-adaptin|sigma-adaptin 3a|sigma3A-adaptin
Swissprots Q53XL4 O00676 O00721 Q6ICQ2 O00727 O00647 Q92572
Accessions EAW48952 EAW48953 Q92572 AK124911 AK126876 AK311843 BAG34785 BC000804 AAH00804 BC012614 BI600357 BT009833 AAP88835 BX647735 CR450341 CAG29337 D63643 BAA09798 DQ891198 ABM82124 DQ894381 ABM85307 U91932 AAD03779 X99458 CAA67823 XM_011543135 XP_011541437 XM_011543136 XP_011541438 XM_011543137 XP_011541439 XM_011543138 XP_011541440 NM_001002924 NM_001284 NP_001275
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity Present in all adult tissues examined. {ECO:0000269|PubMed:8697810, ECO:0000269|PubMed:9118953, ECO:0000269|PubMed:9151686}.
Top Pathways Lysosome

AP-3σ siRNA (h) - sc-60180 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP-3σ shRNA Plasmid (h) - sc-60180-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP-3σ shRNA (h) Lentiviral Particles - sc-60180-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AP3S1 RNAi - H00001176-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU107671 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3297 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3297 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05321 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05321

AP3S1 siRNA (Human) - CRH0839 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AP3S1 RNAi - H00001176-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AP3S1 - MBS8238728 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AP3S1(NM_001284.2) - SHG063745 from Creative biogene

Category siRNA
Species Reactivities Human

Human AP3S1 siRNA - orb261341 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AP3S1 shRNA Plasmid (Human) - CHH0839 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AP3S1 miRNA 3'UTR clone - MiUTR1H-00445 from Creative biogene

Species Reactivities Human
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