AP3S1

Gene Symbol	AP3S1
Entrez Gene	1176
Alt Symbol	CLAPS3, Sigma3A
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 3, sigma 1 subunit
Other Description	AP-3 complex sigma-3A subunit|AP-3 complex subunit sigma-1|AP-3 complex subunit sigma-3A|adapter-related protein complex 3 sigma-1 subunit|adapter-related protein complex 3 subunit sigma-1|adaptor-related protein complex 3 subunit sigma-1|clathrin-associated/assembly/adapter protein, small 3|clathrin-associated/assembly/adaptor protein, small 3 (22kD)|sigma-3A-adaptin|sigma-adaptin 3a|sigma3A-adaptin
Swissprots	Q53XL4 O00676 O00721 Q6ICQ2 O00727 O00647 Q92572
Accessions	EAW48952 EAW48953 Q92572 AK124911 AK126876 AK311843 BAG34785 BC000804 AAH00804 BC012614 BI600357 BT009833 AAP88835 BX647735 CR450341 CAG29337 D63643 BAA09798 DQ891198 ABM82124 DQ894381 ABM85307 U91932 AAD03779 X99458 CAA67823 XM_011543135 XP_011541437 XM_011543136 XP_011541438 XM_011543137 XP_011541439 XM_011543138 XP_011541440 NM_001002924 NM_001284 NP_001275
Function	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location	Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity	Present in all adult tissues examined. {ECO:0000269|PubMed:8697810, ECO:0000269|PubMed:9118953, ECO:0000269|PubMed:9151686}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AP3S1 protein (His-DHFR tag) - ab127867 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

Human AP3S1 full length protein - ab137169 from Abcam Category Protein Prices $345.00 Sizes 100 µg Source E. coli Species Human

AP3S1 Antibody Blocking Peptide - LS-E262 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AP3S1 Antibody Blocking Peptide - LS-E18635 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AP3S1 Antibody Blocking Peptide - LS-E31135 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

AP3S1 Recombinant Protein - H00001176-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AP3S1 Protein - NBP2-22678 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

AP3S1 Blocking Peptide - NBP1-76588PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

AP3S1-Antibody-N-term-Blocking-Peptide - BP10499a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human AP3S1 protein - orb167898 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

AP3S1 Blocking Peptide - 33R-3908 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AP3S1 Blocking Peptide - 33R-4012 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AP3S1 protein (His tag) - 80R-2581 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

AP3 complex subunit sigma-1 / AP3S1 (1-193, His-tag) - AR50627PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

AP3 complex subunit sigma-1 / AP3S1 (1-193, His-tag) - AR50627PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

AP3 complex subunit sigma-1 - H00001176-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AP3 complex subunit sigma-1 - H00001176-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AP3 complex subunit sigma-1 control peptide - AP26157CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

AP3S1, 1-193aa, Human, His tag, E.coli - 01-P1803 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

AP3S1 Peptide - 6391P from ProSci Category Peptide Species Human

AP3S1 Human - PRPS-1287 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human adaptor-related protein complex 3, sigma 1 subunit, His-tagged - AP3S1-364H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human AP-3 complex subunit sigma-1(AP3S1) - CSB-YP838783HU CSB-EP838783HU CSB-BP838783HU CSB-MP838783HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

AP3S1, 1-193aa, Human, His tag, E.coli - ATGP1803 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

AP-3 complex subunit sigma-1 (AP3S1) , Recombinant Protein - MBS1477502 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,865.00, $1,865.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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