Gene Symbol | Itgae |
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Entrez Gene | 16407 |
Alt Symbol | A530055J10, CD103, aM290, alpha-E1, alpha-M290 |
Species | Mouse |
Gene Type | protein-coding |
Description | integrin alpha E, epithelial-associated |
Other Description | integrin alpha M290|integrin alpha-E |
Swissprots | Q60677 B1AUD5 |
Accessions | AAK30302 BAB00639 EDL12709 Q60677 AK040983 BAC30769 AK154021 BAE32321 AV204610 BC150690 AAI50691 BF453582 CF983010 DQ386608 ABD49099 U12236 AAC52142 XM_006536289 XP_006536352 NM_172944 NP_766532 NM_008399 NP_032425 |
Function | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Regulation of actin cytoskeleton |
Anti-CD103 antibody [2E7] - Low endotoxin, Azide free - ab171224 from Abcam
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Anti-Integrin alpha E antibody [2E7] - ab25198 from Abcam
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Anti-Integrin alpha E antibody [2E7] (Allophycocyanin) - ab93501 from Abcam
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Anti-Integrin alpha E antibody [2E7] (Biotin) - ab25211 from Abcam
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Anti-Integrin alpha E antibody [2E7] (FITC) - ab24938 from Abcam
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Anti-Integrin alpha E antibody [2E7] (Phycoerythrin) - ab25517 from Abcam
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Anti-Integrin alpha E antibody [AP-MAB0828] - ab83052 from Abcam
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Integrin alpha E/CD103 Antibody (RM0065-7A3) - NBP2-12139 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (262523) - MAB1990 from Novus Biologicals
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Integrin alpha E/CD103 Antibody - AF1990 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (2E7) - NBP1-28123 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (AP-MAB0828) - NBP1-06674 from Novus Biologicals
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Integrin alpha E/CD103 Antibody [Biotin] - BAF1990 from Novus Biologicals
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Integrin alpha E/CD103 Antibody [Alexa Fluor 488] - FAB1990G from Novus Biologicals
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Integrin alpha E/CD103 Antibody [PE] - FAB1990P from Novus Biologicals
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Integrin alpha E/CD103 Antibody [Allophycocyanin] - FAB1990A from Novus Biologicals
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Integrin alpha E/CD103 Antibody (2E7) [Biotin] - NBP1-28125 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (2E7) [FITC] - NBP1-28124 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (2E7) [PE] - NBP1-28126 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [PerCP] - NBP2-12139PCP from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [Alexa Fluor (R) 700] - NBP2-12139AF700 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [Alexa Fluor (R) 647] - NBP2-12139AF647 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [Alexa Fluor (R) 488] - NBP2-12139AF488 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [Alexa Fluor (R) 405] - NBP2-12139AF405 from Novus Biologicals
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Integrin alpha E/CD103 Antibody (RM0065-7A3) [DyLight 350] - NBP2-12139UV from Novus Biologicals
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