Itgae

Gene Symbol Itgae
Entrez Gene 16407
Alt Symbol A530055J10, CD103, aM290, alpha-E1, alpha-M290
Species Mouse
Gene Type protein-coding
Description integrin alpha E, epithelial-associated
Other Description integrin alpha M290|integrin alpha-E
Swissprots Q60677 B1AUD5
Accessions AAK30302 BAB00639 EDL12709 Q60677 AK040983 BAC30769 AK154021 BAE32321 AV204610 BC150690 AAI50691 BF453582 CF983010 DQ386608 ABD49099 U12236 AAC52142 XM_006536289 XP_006536352 NM_172944 NP_766532 NM_008399 NP_032425
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Regulation of actin cytoskeleton

Mouse Itgae ORF Clone(NM_008399.2) - CDCR245421 from Creative Biomart

Species Mouse
Accession NM_008399.2

Mouse Itgae ORF Clone(NM_008399.2) - CDCR245422 from Creative Biomart

Species Mouse
Accession NM_008399.2

Mouse Itgae ORF Clone(NM_172944.2) - CDCR271911 from Creative Biomart

Species Mouse
Accession NM_172944.2

Mouse Itgae ORF Clone(NM_172944.2) - CDCR271912 from Creative Biomart

Species Mouse
Accession NM_172944.2

Mouse ITGAE ORF clone(NM_172944.2) - CDCH387386 from Creative Biomart

Species Mouse
Accession NM_172944.2

Mouse ITGAE ORF clone(NM_008399.2) - CDCH387387 from Creative Biomart

Species Mouse
Accession NM_008399.2

Mouse Itgae ORF Clone(NM_172944.2) - CDCR271911 from Creative biogene

Species Mouse

Human Itgae ORF clone (NM_008399.2) - CDCL151182 from Creative biogene

Species Mouse

Mouse Itga7 cDNA Clone(NM_008398.2) - CDFG022268 from Creative biogene

Species Mouse
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