Gene Symbol | Vcam1 |
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Entrez Gene | 25361 |
Alt Symbol | VCAM1B |
Species | Rat |
Gene Type | protein-coding |
Description | vascular cell adhesion molecule 1 |
Other Description | V-CAM 1|VCAM-1|vascular cell adhesion protein 1 |
Swissprots | P29534 Q63669 Q5FVS3 |
Accessions | EDL82023 P29534 BC089812 AAH89812 M84488 AAA42332 X63722 CAA45254 NM_012889 NP_037021 |
Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. |
Top Pathways | Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection |
VCAM-1 (MR106) - sc-53548 from Santa Cruz Biotechnology
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Anti-VCAM1 antibody [MR106] - ab95541 from Abcam
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Anti-VCAM1 antibody [MR106] (Biotin) - ab95542 from Abcam
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VCAM-1/CD106 Antibody (MR106) - NBP1-43368 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Allophycocyanin] - NBP1-43368APC from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [PE] - NBP1-43368PE from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 350] - NBP1-43368UV from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 680] - NBP1-43368FR from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [7C] - NBP1-43368V2 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Alexa Fluor (R) 700] - NBP1-43368AF700 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Alexa Fluor (R) 647] - NBP1-43368AF647 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Alexa Fluor (R) 488] - NBP1-43368AF488 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Alexa Fluor (R) 405] - NBP1-43368AF405 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 405] - NBP1-43368V from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [PerCP] - NBP1-43368PCP from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 488] - NBP1-43368G from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 405LS] - NBP1-43368V3 from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [DyLight 755] - NBP1-43368IR from Novus Biologicals
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VCAM-1/CD106 Antibody (MR106) [Biotin] - NBP1-43597 from Novus Biologicals
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Vcam1 Antibody (OASA03810) - OASA03810 from Aviva Systems Biology
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Vcam1 Antibody (OASA03811) - OASA03811 from Aviva Systems Biology
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Vcam1 Antibody (OASA03812) - OASA03812 from Aviva Systems Biology
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Vcam1 Antibody - FITC Conjugated (OASA03813) - OASA03813 from Aviva Systems Biology
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Vcam1 Antibody - FITC Conjugated (OASA03814) - OASA03814 from Aviva Systems Biology
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Vcam1 Antibody - PE Conjugated (OASA03815) - OASA03815 from Aviva Systems Biology
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