Gene Symbol | Vcam1 |
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Entrez Gene | 25361 |
Alt Symbol | VCAM1B |
Species | Rat |
Gene Type | protein-coding |
Description | vascular cell adhesion molecule 1 |
Other Description | V-CAM 1|VCAM-1|vascular cell adhesion protein 1 |
Swissprots | P29534 Q63669 Q5FVS3 |
Accessions | EDL82023 P29534 BC089812 AAH89812 M84488 AAA42332 X63722 CAA45254 NM_012889 NP_037021 |
Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. |
Top Pathways | Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection |
Rat VCAM1 protein - orb245661 from Biorbyt
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Rat VCAM1 Protein - abx069624 from Abbexa
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Vascular Cell Adhesion Molecule 1 (VCAM1), Rat - 20-6766 from ARP American Research Products
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Recombinant rat Vascular cell adhesion protein 1 - CSB-EP167294r CSB-BP167294r CSB-MP167294r from Cusabio
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Recombinant Rat Vascular cell adhesion protein 1(Vcam1),partial - CSB-RP167294r from Cusabio
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Recombinant Rat Vascular cell adhesion protein 1(Vcam1) - CSB-YP025809RA CSB-EP025809RA CSB-BP025809RA CSB-MP025809RA from Cusabio
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Vascular Cell Adhesion Molecule 1 (VCAM1) - RPU144309 from Biomatik
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Vascular Cell Adhesion Molecule 1 (VCAM1), Recombinant Protein - MBS2018641 from MyBioSource
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Vascular cell adhesion protein 1 (Vcam1) , Recombinant Protein - MBS952069 from MyBioSource
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Recombinant Rat VCAM1 Protein - VCAM1-6505R from Creative Biomart
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Recombinant Vascular Cell Adhesion Molecule 1 (VCAM1) - RPU44309 from Biomatik
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VCAM1 Recombinant Protein (OPCD07871) - OPCD07871 from Aviva Systems Biology
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Recombinant rat Vascular cell adhesion protein 1 - AP72332 from Signalway Antibody
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