F11R

Gene Symbol F11R
Entrez Gene 50848
Alt Symbol CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species Human
Gene Type protein-coding
Description F11 receptor
Other Description junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule 1
Swissprots B7Z941 Q9Y624
Accessions AAO84556 CAF86420 CAH05313 CAH05314 EAW52677 EAW52678 EAW52680 EAW52681 EAW52682 EAW52683 Q9Y624 AF154005 AAD43794 AF172398 AAD48877 AF207907 AAF22829 AK026665 AK075152 BAC11436 AK299487 BAH13047 AK304412 BAH14177 AL136649 CAB66584 AL365518 AY358896 AAQ89255 BC001533 AAH01533 BT020103 AAV38906 CR533512 CAG38543 DA907460 DQ892228 ABM83154 DQ895428 ABM86354 EU831648 ACE87248 EU831732 ACE86566 NM_016946 NP_058642 NM_144501 NM_144502 NM_144503 NM_144504
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. {ECO:0000250}.
Subcellular Location Cell junction, tight junction {ECO:0000269|PubMed:11171323}. Cell membrane {ECO:0000269|PubMed:11171323}; Single-pass type I membrane protein {ECO:0000269|PubMed:11171323}. Note=Localized at tight junctions of both epithelial and endothelial cells.
Top Pathways Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

JAM-A (1H2A9) - sc-53624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JAM-A (1H2A9): sc-53624. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

JAM-A (C-15) - sc-17427 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

JAM-A (H-80) - sc-25629 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
JAM-A (H-80): sc-25629. Western blot analysis of JAM-A expression in human platelet extract.

JAM-A (J10.4) - sc-53623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JAM-A (J10.4): sc-53623. Western blot analysis of JAM-A expression in human platelet extract (A,D) and human PBL (B,E) and T84 (C,F) whole cell lysates under reducing (A,B,C) and non-reducing (D,E,F) conditions.

JAM-A (J3F.1) - sc-53622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JAM-A (J3F.1): sc-53622. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

JAM-A (M.Ab.F11) - sc-52690 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
JAM-A (M.Ab.F11): sc-52690. Indirect FCM analysis of human peripheral blood leukocytes stained with JAM-A (M.Ab.F11), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

JAM-A (43) - sc-135956 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
JAM-A (43): sc-135956. Western blot analysis of JAM-A expression in human endothelial whole cell lysate.

Anti-Junctional Adhesion Molecule 1 antibody - ab180821 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of HeLa cells using ab180821. Blue DAPI for nuclear staining.

Anti-Junctional Adhesion Molecule 1 antibody - ab91501 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Junctional Adhesion Molecule 1 antibody (ab91501) at 0.3 µg/ml + Human Peripheral Blood Mononucleocyte lysate at 35 µg

Anti-Junctional Adhesion Molecule 1 antibody - ab106114 from Abcam

Prices $372.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Junctional Adhesion Molecule 1 antibody - ab89203 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Junctional Adhesion Molecule 1 antibody (ab89203) at 1/500 dilution + Human spleen lysate at 50 µg

Anti-Junctional Adhesion Molecule 1 antibody - ab101978 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Junctional Adhesion Molecule 1 antibody (ab101978) at 0.4 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 5 µgLane 4 : HeLa whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Junctional Adhesion Molecule 1 antibody - ab116354 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Junctional Adhesion Molecule 1 antibody (ab116354) at 1 µg/ml + HeLa cell lysate at 10 µg

Anti-Junctional Adhesion Molecule 1 antibody [6E11] - ab140510 from Abcam

Host Mouse
Clonality Monoclonal
Clone 6E11
Immunofluorescent analysis of COS7 cells transiently transfected with pCMV6-ENTRY Junctional Adhesion Molecule 1, labelling Junctional Adhesion Molecule 1 with ab140510 at 1/100 dilution.

Anti-Junctional Adhesion Molecule 1 antibody [EP1042Y] - ab52647 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1042Y
Anti-Junctional Adhesion Molecule 1 antibody [EP1042Y] (ab52647) at 1/2000 dilution + Hela cell lysate at 10 µgSecondaryGoat anti-rabbit HRP labeled at 1/2000 dilution

Anti-Junctional Adhesion Molecule 1 antibody [M.Ab.F11] - ab17261 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone M.Ab.F11

Anti-Junctional Adhesion Molecule 1 antibody [MM0785-60M31] - ab201562 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0785-60M31

JAM-A Antibody [Unconjugated] - AF1103 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
JAM‑A was detected in immersion fixed MCF‑7 human breast cancer cell line using Goat Anti-Human JAM‑A Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1103) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # NL003) and counterstained with DAPI (blue). Specific staining was localized to intercellular junctions. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

JAM-A Antibody (654806) - MAB1103 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 654806
Immunohistochemistry JAM-A Antibody (654806)

JAM-A Antibody (2E3-1C8) - H00050848-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E3-1C8
Western Blot: JAM-A Antibody (2E3-1C8) [H00050848-M01] - F11R monoclonal antibody (M01), clone 2E3-1C8 Analysis of F11R expression in HepG2.

JAM-A Antibody - NBP1-49908 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: JAM-A Antibody [NBP1-49908] - Samples: Whole cell lysate from 293T (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-JAM-A antibody NBP1-49908 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. JAM-A was not successfully immunoprecipitated by rabbit anti-JAM-A antibody NBP1-49907, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A and B).

JAM-A Antibody - H00050848-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

JAM-A Antibody - NBP2-38934 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934] - Staining of human oral mucosa shows moderate cell membranous positivity in squamous epithelial cells.

JAM-A Antibody - NBP1-36743 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: JAM-A Antibody [NBP1-36743] - (0.3ug/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

JAM-A Antibody - H00050848-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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