F11R

Gene Symbol	F11R
Entrez Gene	50848
Alt Symbol	CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species	Human
Gene Type	protein-coding
Description	F11 receptor
Other Description	junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule 1
Swissprots	B7Z941 Q9Y624
Accessions	AAO84556 CAF86420 CAH05313 CAH05314 EAW52677 EAW52678 EAW52680 EAW52681 EAW52682 EAW52683 Q9Y624 AF154005 AAD43794 AF172398 AAD48877 AF207907 AAF22829 AK026665 AK075152 BAC11436 AK299487 BAH13047 AK304412 BAH14177 AL136649 CAB66584 AL365518 AY358896 AAQ89255 BC001533 AAH01533 BT020103 AAV38906 CR533512 CAG38543 DA907460 DQ892228 ABM83154 DQ895428 ABM86354 EU831648 ACE87248 EU831732 ACE86566 NM_016946 NP_058642 NM_144501 NM_144502 NM_144503 NM_144504
Function	Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. {ECO:0000250}.
Subcellular Location	Cell junction, tight junction {ECO:0000269|PubMed:11171323}. Cell membrane {ECO:0000269|PubMed:11171323}; Single-pass type I membrane protein {ECO:0000269|PubMed:11171323}. Note=Localized at tight junctions of both epithelial and endothelial cells.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Junctional Adhesion Molecule 1 full length protein - ab132180 from Abcam Category Protein Source Wheat germ Species Human

Human Junctional Adhesion Molecule 1 protein fragment - ab126670 from Abcam Category Protein Source E. coli Species Human

Human Junctional Adhesion Molecule 1 protein fragment - ab151859 from Abcam Category Protein Source HEK 293 cells Species Human

JAM-A Recombinant Protein - H00050848-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human JAM-A Protein - NBP1-98971 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

JAM-A Recombinant Protein - H00050848-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

JAM-A blocking peptide - GTX88380-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

Recombinant Human JAM-A Fc Chimera, CF - 1103-JM-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human F11R protein - orb168321 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human JAMA Fc tag protein - orb83058 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human JAMA His tag protein - orb83243 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human JAMA protein - orb49486 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

F11R Blocking Peptide - 33R-10308 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

F11R Blocking Peptide - 33R-10403 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

F11R protein (His tag) - 80R-2296 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

Junctional Adhesion Molecule 1 Peptide - AC21-1934-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD321 / JAM1 (26-238, His-tag) - AR50380PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CD321 / JAM1 (26-238, His-tag) - AR50380PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CD321 / JAM1 - H00050848-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD321 / JAM1 - H00050848-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD321 / JAM1 - H00050848-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

F11R, 26-238aa, Human, His tag, E.coli - 01-P1556 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Junctional Adhesion Molecule A, JAM-A, Human, Recombinant - 19-C468 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source HEK293 Species Human

F11R Peptide - 42-104P from ProSci Category Peptide Species Human

F11R fusion protein - ag8751 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

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