F11R

Gene Symbol F11R
Entrez Gene 50848
Alt Symbol CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species Human
Gene Type protein-coding
Description F11 receptor
Other Description junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule 1
Swissprots B7Z941 Q9Y624
Accessions AAO84556 CAF86420 CAH05313 CAH05314 EAW52677 EAW52678 EAW52680 EAW52681 EAW52682 EAW52683 Q9Y624 AF154005 AAD43794 AF172398 AAD48877 AF207907 AAF22829 AK026665 AK075152 BAC11436 AK299487 BAH13047 AK304412 BAH14177 AL136649 CAB66584 AL365518 AY358896 AAQ89255 BC001533 AAH01533 BT020103 AAV38906 CR533512 CAG38543 DA907460 DQ892228 ABM83154 DQ895428 ABM86354 EU831648 ACE87248 EU831732 ACE86566 NM_016946 NP_058642 NM_144501 NM_144502 NM_144503 NM_144504
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. {ECO:0000250}.
Subcellular Location Cell junction, tight junction {ECO:0000269|PubMed:11171323}. Cell membrane {ECO:0000269|PubMed:11171323}; Single-pass type I membrane protein {ECO:0000269|PubMed:11171323}. Note=Localized at tight junctions of both epithelial and endothelial cells.
Top Pathways Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

F11R 293T Cell Transient Overexpression Lysate(Denatured) - H00050848-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

JAM-A Overexpression Lysate (Native) - NBL1-10405 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Junctional Adhesion Molecule 1 Overexpression Lysate (Adult Normal) [NBL1-10405] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Junctional Adhesion Molecule 1.

JAM-A Overexpression Lysate (Native) - NBL1-10404 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Junctional Adhesion Molecule 1 Overexpression Lysate (Adult Normal) [NBL1-10404] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Junctional Adhesion Molecule 1.

JAM-A Overexpression Lysate (Native) - NBP2-06988 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Junctional Adhesion Molecule 1 Overexpression Lysate (Adult Normal) [NBP2-06988] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Junctional Adhesion Molecule 1.

F11R Over-expression Lysate Product - GWB-A4E8CA from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

F11R Over-expression Lysate Product - GWB-544716 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

JAM-A Overexpression Lysate (Native) - NBP2-11275 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Junctional Adhesion Molecule 1 Overexpression Lysate (Adult Normal) [NBP2-11275] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Junctional Adhesion Molecule 1.

JAM-A Overexpression Lysate (Denatured) - H00050848-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

JAM-A Overexpression Lysate (Denatured) - H00050848-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human F11R Knockdown Stable Cell Line - CSC-DC005166 from Creative biogene

Category Cell Line
Species Human
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