F11R

Gene Symbol F11R
Entrez Gene 50848
Alt Symbol CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1
Species Human
Gene Type protein-coding
Description F11 receptor
Other Description junctional adhesion molecule 1|junctional adhesion molecule A|platelet F11 receptor|platelet adhesion molecule 1
Swissprots B7Z941 Q9Y624
Accessions AAO84556 CAF86420 CAH05313 CAH05314 EAW52677 EAW52678 EAW52680 EAW52681 EAW52682 EAW52683 Q9Y624 AF154005 AAD43794 AF172398 AAD48877 AF207907 AAF22829 AK026665 AK075152 BAC11436 AK299487 BAH13047 AK304412 BAH14177 AL136649 CAB66584 AL365518 AY358896 AAQ89255 BC001533 AAH01533 BT020103 AAV38906 CR533512 CAG38543 DA907460 DQ892228 ABM83154 DQ895428 ABM86354 EU831648 ACE87248 EU831732 ACE86566 NM_016946 NP_058642 NM_144501 NM_144502 NM_144503 NM_144504
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. {ECO:0000250}.
Subcellular Location Cell junction, tight junction {ECO:0000269|PubMed:11171323}. Cell membrane {ECO:0000269|PubMed:11171323}; Single-pass type I membrane protein {ECO:0000269|PubMed:11171323}. Note=Localized at tight junctions of both epithelial and endothelial cells.
Top Pathways Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

F11R - MBS1278458 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC001533

Human F11R ORF Clone(NM_016946.4) - CDCL162790 from Creative Biomart

Species Human
Accession NM_016946.4

Human JAM-A ORF clone(NM_016946.4) - CDCL185011 from Creative biogene

Species Human

Human F11R ORF Clone (BC001533) - CDCS414379 from Creative biogene

Species Human
Accession Q6FIB4

Human JAMA gene - orb90795 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human JAM-A (NP_058642) VersaClone cDNA - RDC1608 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Human

Mouse JAM-A (NP_766235) VersaClone cDNA - RDC2155 from R&D Systems

Prices $199.00
Sizes 10 µg
Species Mouse
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