Gene Symbol | S1pr4 |
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Entrez Gene | 13611 |
Alt Symbol | Edg6, Lpc1, S1p4 |
Species | Mouse |
Gene Type | protein-coding |
Description | sphingosine-1-phosphate receptor 4 |
Other Description | S1P receptor Edg-6|S1p receptor 4|endothelial differentiation G-protein coupled receptor 6|endothelial differentiation G-protein-coupled receptor 6|lysophospholipid receptor C1|sphingosine 1-phosphate receptor 4|sphingosine 1-phosphate receptor Edg-6 |
Swissprots | Q8K1R9 Q8C6E2 Q9Z0L1 Q3U4H3 |
Accessions | CAD33254 EDL31402 Q9Z0L1 AJ006074 CAA06847 AK075854 AK154242 BAE32458 BC107000 AAI07001 NM_010102 NP_034232 |
Function | Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Specifically expressed in fetal and adult lymphoid and hematopoietic tissue. Expressed in lung, spleen, thymus and lymph node but absent in other non-lymphatic tissue. Coexpressed with GNA15 at the same relative levels in all tissues examined, with the highest levels in adult spleen and lung. {ECO:0000269|PubMed:12401211}. |
Top Pathways | Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction |
Annexin A1 (ANXA1), Mouse, ELISA Kit - CSB-EL001836MO from ARP American Research Products
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Sphingosine 1-phosphate receptor 4, S1pr4, Mouse, ELISA Kit - E0327m from ARP American Research Products
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Mouse S1PR4(Sphingosine 1 Phosphate Receptor 4) ELISA Kit - E-EL-M2625 from Elabscience
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sphingosine-1-phosphate receptor 4, ELISA Kit - MBS9316706 from MyBioSource
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ELISA Kit for Sphingosine 1 Phosphate Receptor 4 (S1PR4) - SEE694Mu from Cloud-clone
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Mouse S1PR4(Sphingosine 1 Phosphate Receptor 4) ELISA Kit - E-EL-M2625 from Iwai North America Inc.
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S1PR4 - EKM2682 from Nordic BioSite
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Mouse S1pr4 ELISA Kit - E066951 from Biobool
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S1PR4 ELISA Kit (Mouse) (OKCD02865) - OKCD02865 from Aviva Systems Biology
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Mouse Sphingosine 1-phosphate receptor 4 (S1PR4) ELISA Kit - AE20859MO from ARP American Research Products
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Sphingosine 1-phosphate receptor 4, ELISA Kit - MBS2882190 from MyBioSource
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