Gene Symbol | Epor |
---|---|
Entrez Gene | 13857 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | erythropoietin receptor |
Other Description | EPO-R |
Swissprots | Q63852 P14753 |
Accessions | AAA37572 AAA37582 CAA37248 EDL25236 P14753 AK010968 AK139031 BAE23871 BB842890 BC003953 AAH03953 BC046282 AAH46282 J04843 AAA37571 XM_006509998 XP_006510061 NM_010149 NP_034279 |
Function | Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. {ECO:0000269|PubMed:8382775, ECO:0000269|PubMed:8617735}. |
Subcellular Location | Isoform EPOR-F: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in relatively mature erythroid progenitor cells and in EPO-responsive erythroleukemia cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway |
Anti-EPOR antibody produced in rabbit - SAB2106668 from Sigma-Aldrich
|
||||||||
Epor antibody - N-terminal region (ARP44217_P050) - ARP44217_P050 from Aviva Systems Biology
|
||||||||
EpoR antibody - 70R-33577 from Fitzgerald
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) - 140167 from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (AP) - 140167-AP from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (APC) - 140167-APC from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (Biotin) - 140167-Biotin from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (FITC) - 140167-FITC from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (HRP) - 140167-HRP from USBiological Life Science
|
||||||||
Anti -Erythropoietin Receptor (EPOr, EPO-R) (PE) - 140167-PE from USBiological Life Science
|
||||||||
EpoR antibody - 70R-34688 from Fitzgerald
|
||||||||
EpoR antibody (Tyr368) - 70R-33576 from Fitzgerald
|
||||||||
Erythropoietin Receptor Antibody - abx102352 from Abbexa
|
||||||||
Anti-Erythropoietin Receptor (EPOR) - 20-2073 from ARP American Research Products
|
||||||||
Epor Antibody - GWB-MP755H from Genway Biotech
|
||||||||
Polyclonal Antibody to Erythropoietin Receptor (EPOR) - PAA027Mu01 from Cloud-clone
|
||||||||
Biotin-Linked Antibody to Erythropoietin Receptor (EPOR) - PAA027Mu71 from Cloud-clone
|
||||||||
Epor-antibody-N-terminal-region-AI12390 - AI12390 from Abgent, a WuXi AppTec company
|
||||||||
EPO Receptor antibody - 70R-49713 from Fitzgerald
|
||||||||
Anti-Human-Erythropoietin-Receptor-Antibody- - ABD11162 from Abgent, a WuXi AppTec company
|
||||||||
EPOR / Erythropoietin Receptor Antibody, Rabbit PAb, Antigen Affinity Purified - 50031-T16-50 from Sino Biological
|
||||||||
Erythropoietin Receptor (EPOR) Polyclonal Antibody - CAU28948 from Biomatik
|
||||||||
Epor antibody - N-terminal region : Biotin (ARP44217_P050-Biotin) - ARP44217_P050-Biotin from Aviva Systems Biology
|
||||||||
Epor antibody - N-terminal region : FITC (ARP44217_P050-FITC) - ARP44217_P050-FITC from Aviva Systems Biology
|
||||||||
Epor antibody - N-terminal region : HRP (ARP44217_P050-HRP) - ARP44217_P050-HRP from Aviva Systems Biology
|