CREB1

Gene Symbol CREB1
Entrez Gene 1385
Alt Symbol CREB
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 1
Other Description CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein
Swissprots P16220 Q9UMA7 Q6V963 P21934
Accessions AAB20597 AAD13869 AAX88961 AAX93174 CAM91158 EAW70405 EAW70406 EAW70407 EAW70408 EAW70409 EAW70410 P16220 AK091534 AK095116 AK123952 AK126342 AK298740 BAH12862 AK302333 BAH13677 AK312747 BAG35615 AK315226 BAG37655 AW205606 AY347527 AAQ24858 BC010636 AAH10636 BC095407 AAH95407 BT019509 AAV38316 CR407617 CAG28545 DC366797 DQ891157 ABM82083 DQ894336 ABM85262 M27691 AAA35715 M34356 AAA35716 S78693 AAB34949 S78695 AAB34950 X55545 CAA39151 X60003 CAA42620 XM_011510645 XP_011508947 XM_011510646 XP_011508948 XM_011510647 XP_011508949 XM_011510648 XP_011508950 XM_011510649 XP_011508951 XM_011510650 XP_011508952 XM_011510651 XP_011508953 XM_011510652 XP_011508954 XM_011510653 XP_011508955 XR_241289 XR_241290 XR_241292 XR_427071 XR_922862 NM_004379 NP_004370 NM_134442 NP_604391
Function Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}.
Top Pathways Prostate cancer, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, TNF signaling pathway

PathScan ® Phospho-CREB (Ser133) Sandwich ELISA Kit - 7385 from Cell Signaling Technology

Category ELISA Kit
Prices $489.00
Sizes 1 kit (96 assays)
Figure 2. The relationship between the protein concentration of lysates from untreated and forskolin-treated SK-N-MC cells and the absorbance at 450 nm using the PathScan ® Phospho-CREB (Ser133) Sandwich ELISA Kit is shown.

PathScan ® Total CREB Sandwich ELISA Kit - 7390 from Cell Signaling Technology

Category ELISA Kit
Prices $489.00
Sizes 1 kit (96 assays)
Figure 2. The relationship between the protein concentration of lysates from untreated and forskolin-treated SK-N-MC cells and the absorbance at 450 nm using the PathScan ® Total CREB Sandwich ELISA Kit is shown.

CREB1 (pS133) + Total CREB1 SimpleStep ELISA™ Kit - ab176659 from Abcam

Category ELISA Kit
Prices $484.00
Sizes 1 x 96 tests
Example of a typical CREB1 (pS133) and CREB1 (Total) cell lysate dilution series. Background-subtracted data values (mean +/- SD) are graphed.

CREB1 (pS133) PhosphoTracer ELISA Kit - ab119623 from Abcam

Category ELISA Kit
Sensitivity 3000 cells/well
Range 3000 cells/well - 100000 cells/well
Detection of CREB1 (pS133) in serum-starved A431 cells treated with varying concentrations of forskolin, using ab119623.

CREB1 (pS133) SimpleStep ELISA™ Kit - ab176638 from Abcam

Category ELISA Kit
Prices $484.00
Sizes 1 x 96 tests
Sensitivity < 0.5 µg/ml
Range 1 µg/ml - 100 µg/ml
Example of a typical CREB1 (pS133) cell lysate dilution series. Background-subtracted data values (mean +/- SD) are graphed.
Using Western blot, CREB1 phosphorylation at Ser133 is detected in EGF-treated A431 cells (+), compared with untreated cells (-), whereas no change in total CREB1 levels was observed.

CREB1 Total PhosphoTracer ELISA Kit - ab119624 from Abcam

Category ELISA Kit
Sensitivity 3000 cells/well
Range 3000 cells/well - 100000 cells/well
PhosphoTracer CREB1 Total ELISA Kit (ab119624) used in Sandwich ELISA. The results show that CREB is readily detectable in several cell lines.

CREB1 Total SimpleStep ELISA™ Kit - ab176639 from Abcam

Category ELISA Kit
Prices $484.00
Sizes 1 x 96 tests
Sensitivity < 1 µg/ml
Range 2 µg/ml - 200 µg/ml
Example of a typical CREB1 cell lysate dilution series. Background-subtracted data values (mean +/- SD) are graphed.

CREB (pS133) Transcription Factor Assay Kit - ab133117 from Abcam

Category Cellular Assay
Prices $494.00
Sizes 96 tests
Detection of CREB (pSer133) on stimulated PC-12 nuclear extracts following treatment with PP2A. This experiment demonstrates the specificity of the CREB (pSer133) primary antibody.

Mouse/Human/Rat Phospho-CREB1 / CREB (Ser133) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1482 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat CREB1 / CREB ELISA Kit (Cell-Based ELISA) - LS-F1911 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-CREB1 / CREB (Ser129) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F861 from LifeSpan Bioscience

Category ELISA Kit
Prices $750.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat CREB1 / CREB ELISA Kit (DNA-Binding ELISA) - LS-F863 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-CREB1 / CREB (Ser133) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F862 from LifeSpan Bioscience

Category ELISA Kit
Prices $750.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human Phospho-CREB1 / CREB (Ser121) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F860 from LifeSpan Bioscience

Category ELISA Kit
Prices $750.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-CREB1 / CREB (Ser142) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1035 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-CREB1 / CREB (Ser121) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1164 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate
Range 0.312-20 ng/ml

Mouse/Human/Rat Phospho-CREB1 / CREB (Thr100) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1655 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate
Range 0.312-20 ng/ml

Rat CREB1 / CREB ELISA Kit (Sandwich ELISA) - LS-F11210 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.312-20 ng/ml

Mouse CREB1 / CREB ELISA Kit (Sandwich ELISA) - LS-F11211 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.078
Range 0.312-20 ng/ml

CREB [p Ser133] Colorimetric Assay Kit - KA1308 from Novus Biologicals

Category Assay Kit
Prices $659.00
Sizes 1 kit

Rabbit anti-CREB Antibody, Affinity Purified - PLA0205 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-CREB Antibody, Affinity Purified: <B>Cat. No. PLA0205</B>: Detection of Human and Mouse CREB by Immunohistochemistry. Sample: FFPE section of Human prostate carcinoma (left) and Mouse teratoma (right). Antibody: Affinity purified Rabbit Anti-CREB (<B>Cat. No. PLA0205</B>) used at a dilution of 1:200 (1 μg/mL). Detection: DAB

Human/Mouse/Rat Phospho-CREB (S133) Cell-Based ELISA - KCB2510 from R&D Systems

Category ELISA Kit
Prices $459.00
Sizes 1 kit

Human/Mouse/Rat Phospho-CREB (S133) DuoSet IC ELISA - DYC2510-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates)
Range 31.20 - 2,000 pg/mL
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