CREB1

Gene Symbol	CREB1
Entrez Gene	1385
Alt Symbol	CREB
Species	Human
Gene Type	protein-coding
Description	cAMP responsive element binding protein 1
Other Description	CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein
Swissprots	P16220 Q9UMA7 Q6V963 P21934
Accessions	AAB20597 AAD13869 AAX88961 AAX93174 CAM91158 EAW70405 EAW70406 EAW70407 EAW70408 EAW70409 EAW70410 P16220 AK091534 AK095116 AK123952 AK126342 AK298740 BAH12862 AK302333 BAH13677 AK312747 BAG35615 AK315226 BAG37655 AW205606 AY347527 AAQ24858 BC010636 AAH10636 BC095407 AAH95407 BT019509 AAV38316 CR407617 CAG28545 DC366797 DQ891157 ABM82083 DQ894336 ABM85262 M27691 AAA35715 M34356 AAA35716 S78693 AAB34949 S78695 AAB34950 X55545 CAA39151 X60003 CAA42620 XM_011510645 XP_011508947 XM_011510646 XP_011508948 XM_011510647 XP_011508949 XM_011510648 XP_011508950 XM_011510649 XP_011508951 XM_011510650 XP_011508952 XM_011510651 XP_011508953 XM_011510652 XP_011508954 XM_011510653 XP_011508955 XR_241289 XR_241290 XR_241292 XR_427071 XR_922862 NM_004379 NP_004370 NM_134442 NP_604391
Function	Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}.
Top Pathways	Prostate cancer, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® CREB siRNA I - 6588 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

SignalSilence ® CREB siRNA II - 6590 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

CREB-1 CRISPR/Cas9 KO Plasmid (h) - sc-400160 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 HDR Plasmid (h) - sc-400160-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 Double Nickase Plasmid (h) - sc-400160-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 Double Nickase Plasmid (h2) - sc-400160-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 CRISPR Activation Plasmid (h) - sc-400160-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 CRISPR Activation Plasmid (h2) - sc-400160-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 Lentiviral Activation Particles (h) - sc-400160-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 Lentiviral Activation Particles (h2) - sc-400160-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB-1 siRNA (h) - sc-29281 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB-1 shRNA Plasmid (h) - sc-29281-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB-1 shRNA (h) Lentiviral Particles - sc-29281-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB-1 siRNA (chicken) - sc-270089 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Bird

CREB-1 shRNA Plasmid (chicken) - sc-270089-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Bird

CREB RNAi - H00001385-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU092951 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6551 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6551 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CREB1 siRNA (Human) - CRH0971 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CREB RNAi - H00001385-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CREB1 - MBS8235675 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CREB1 (NM_004379.3) - SHH269285 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CREB1(NM_004379.3) - SHG198015 from Creative biogene Category siRNA Species Reactivities Human

Human CREB1 siRNA - orb261473 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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