CREB1

Gene Symbol CREB1
Entrez Gene 1385
Alt Symbol CREB
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 1
Other Description CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein
Swissprots P16220 Q9UMA7 Q6V963 P21934
Accessions AAB20597 AAD13869 AAX88961 AAX93174 CAM91158 EAW70405 EAW70406 EAW70407 EAW70408 EAW70409 EAW70410 P16220 AK091534 AK095116 AK123952 AK126342 AK298740 BAH12862 AK302333 BAH13677 AK312747 BAG35615 AK315226 BAG37655 AW205606 AY347527 AAQ24858 BC010636 AAH10636 BC095407 AAH95407 BT019509 AAV38316 CR407617 CAG28545 DC366797 DQ891157 ABM82083 DQ894336 ABM85262 M27691 AAA35715 M34356 AAA35716 S78693 AAB34949 S78695 AAB34950 X55545 CAA39151 X60003 CAA42620 XM_011510645 XP_011508947 XM_011510646 XP_011508948 XM_011510647 XP_011508949 XM_011510648 XP_011508950 XM_011510649 XP_011508951 XM_011510650 XP_011508952 XM_011510651 XP_011508953 XM_011510652 XP_011508954 XM_011510653 XP_011508955 XR_241289 XR_241290 XR_241292 XR_427071 XR_922862 NM_004379 NP_004370 NM_134442 NP_604391
Function Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}.
Top Pathways Prostate cancer, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, TNF signaling pathway

CREB + CREM peptide - ab5860 from Abcam

Category Peptide
Prices $181.00
Sizes 50 µg

CREB (phospho S133) peptide - ab182754 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg

CREB peptide - ab4963 from Abcam

Category Peptide
Prices $181.00
Sizes 50 µg

Human CREB (phospho S133) peptide - ab38313 from Abcam

Category Peptide
All lanes : Anti-CREB (phospho S133) antibody ( ab37714 ) at 1 µg/ml Lane 1 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 2 : NIH 3T3 treated with Vanadate and PDGF Whole Cell Lysate Lane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate with Human CREB (phospho S133) peptide (ab38313) at 1 µg/ml Lane 4 : NIH 3T3 treated with Vanadate and PDGF Whole Cell Lysate with Human CREB (phospho S133) peptide (ab38313) at 1 µg/ml Lane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate with Human CREB peptide ( ab42655 ) at 1 µg/ml Lane 6 : NIH 3T3 treated with Vanadate and PDGF Whole Cell Lysate with Human CREB peptide ( ab42655 ) at 1 µg/ml Lysates/proteins at 10 µg per lane. Secondary Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution Performed under reducing conditions. Predicted band size : 37 kDa Observed band size : 40 kDa ( why is the actual band size different from the predicted? )

Human CREB peptide - ab42655 from Abcam

Category Peptide

Human CREB protein fragment - ab176930 from Abcam

Category Protein
Source E. coli
Species Human
SDS-PAGE analysis of ab176930. Lane 1: 5 µg of ab176930 Lane 2: 2 µg of ab176930

Rat CREB protein fragment - ab43602 from Abcam

Category Protein
Source E. coli
Species Rat

CREB1 / CREB Antibody Blocking Peptide - LS-E1169 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E10913 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E10582 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E14444 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E14445 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E7268 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CREB1 / CREB Antibody Blocking Peptide - LS-E13435 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CREB Protein - H00001385-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human
SDS-Page: CREB Recombinant Protein [H00001385-P01]

Recombinant Human CREB Protein - H00001385-Q02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human CREB Protein - H00001385-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CREB Peptide - P1305 from Novus Biologicals

Category Peptide
Species Human

CREB1-Antibody-Center-Blocking-peptide - BP11707c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Phospho-CREBS133-Antibody-Blocking-peptide - BP3077a from Abgent, a WuXi AppTec company

Category Peptide
Prices $120.00
Sizes 100 µg

AIBZIP blocking peptide - GTX89773-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

Human CREB1 protein (MBP Tag) - orb138620 from Biorbyt

Category Protein
Prices $264.00, $383.00
Sizes 20 μg, 50 μg
Source E. coli
Species Human

Human CREB1 protein - orb244129 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

CREB1 peptide - orb217132 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Zebrafish, Cat

CREB Blocking Peptide - 33R-10725 from Fitzgerald

Category Peptide
Prices $145.00
Sizes 50 µg
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