CREB1

Gene Symbol CREB1
Entrez Gene 1385
Alt Symbol CREB
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 1
Other Description CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein
Swissprots P16220 Q9UMA7 Q6V963 P21934
Accessions AAB20597 AAD13869 AAX88961 AAX93174 CAM91158 EAW70405 EAW70406 EAW70407 EAW70408 EAW70409 EAW70410 P16220 AK091534 AK095116 AK123952 AK126342 AK298740 BAH12862 AK302333 BAH13677 AK312747 BAG35615 AK315226 BAG37655 AW205606 AY347527 AAQ24858 BC010636 AAH10636 BC095407 AAH95407 BT019509 AAV38316 CR407617 CAG28545 DC366797 DQ891157 ABM82083 DQ894336 ABM85262 M27691 AAA35715 M34356 AAA35716 S78693 AAB34949 S78695 AAB34950 X55545 CAA39151 X60003 CAA42620 XM_011510645 XP_011508947 XM_011510646 XP_011508948 XM_011510647 XP_011508949 XM_011510648 XP_011508950 XM_011510649 XP_011508951 XM_011510650 XP_011508952 XM_011510651 XP_011508953 XM_011510652 XP_011508954 XM_011510653 XP_011508955 XR_241289 XR_241290 XR_241292 XR_427071 XR_922862 NM_004379 NP_004370 NM_134442 NP_604391
Function Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}.
Top Pathways Prostate cancer, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, TNF signaling pathway

Phospho-CREB (Ser133) (87G3) Rabbit mAb (Alexa Fluor ® 647 Conjugate) - 14001 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone 87G3
Confocal immunofluorescent analysis of p14 rat brain dentate gyrus using Phospho-CREB (Ser133) (87G3) Rabbit mAb (Alexa Fluor ® 647 Conjugate) (blue pseudocolor). Actin filaments were labeled with Alexa Fluor ® 488 Phalloidin #8878 (green). Red pseudocolor = Propidium Iodide (PI)/RNase Staining Solution #4087. Views shown are 10X magnification (left) and 60X magnification (right).

Phospho-CREB (Ser133) (87G3) Rabbit mAb (Biotinylated) - 4095 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 87G3
Western blot analysis of extracts from SK-N-MC cells, untreated or Forskolin- and IBMX-treated, using Phospho-CREB (Ser133) (87G3) Rabbit mAb (Biotinylated).

Phospho-CREB (Ser133) (87G3) Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 9187 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone 87G3
Confocal immunofluorescent analysis of P14 rat cerebellum, untreated (left) or phosphatase treated (right), labeled with Phospho-CREB (Ser133) (87G3) Rabbit mAb (Alexa Fluor® 488 Conjugate) (green) and GFAP (GA5) Mouse mAb #3670 (red). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye).

Phospho-CREB (Ser133) (87G3) Rabbit mAb (PE Conjugate) - 14228 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone 87G3
Flow cytometric analysis of serum-starved SK-N-MC cells, untreated (blue) or IBMX and Forskolin #3828-treated (0.5 mM and 30 μM, 30 min; green), using Phospho-CREB (Ser133) (87G3) Rabbit mAb (PE Conjugate).

CREB (48H2) Rabbit mAb (Biotinylated) - 4034 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 48H2
Western blot analysis of extracts from NIH/3T3 and SK-N-MC cells using CREB (48H2) Rabbit mAb (Biotinylated) and developed using Streptavidin-HRP #3999.

PhosphoPlus® CREB (Ser133) Antibody Kit - 9190 from Cell Signaling Technology

Prices $489.00
Sizes 1 kit (10 western blots)
Clonality Polyclonal

Phospho-CREB (Ser133) (1B6) Mouse mAb - 9196 from Cell Signaling Technology

Prices $287.00, $678.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Mouse
Clonality Monoclonal
Clone 1B6
Western blot analysis of extracts from SK-N-MC cells, untreated or treated with forskolin and FGF(lanes 1 and 2) or 293 cells. untreated or UV treated (lanes 3 and 4), using Phospho-CREB (Ser133) (1B6) Mouse mAb.

Phospho-CREB (Ser133) (87G3) Rabbit mAb - 9198 from Cell Signaling Technology

Prices $307.00, $719.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Monoclonal
Clone 87G3
Western blot analysis of extracts from SK-N-MC cells, untreated or forskolin- and FGF-treated, using Phospho-CREB (Ser133) (87G3) Rabbit mAb (upper) or CREB (48H2) Rabbit mAb #9197 (lower).

CREB (86B10) Mouse mAb - 9104 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 86B10
Western blot analysis of extracts from 293, COS and PC12 cells, using CREB (86B10) Mouse mAb.

CREB (D76D11) Rabbit mAb - 4820 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D76D11
Western blot analysis of extracts from various cell lines using CREB (D76D11) Rabbit mAb.

CREB (48H2) Rabbit mAb - 9197 from Cell Signaling Technology

Prices $99.00, $256.00, $637.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Monoclonal
Clone 48H2
Western Blot analysis of extracts from SK-N-MC, COS, NIH/3T3, C6 and Drosophila S2 cells, using CREB (48H2) Rabbit mAb.

Phospho-CREB (Ser133) Antibody - 9191 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Phospho-CREB (Ser133) (D1G6) Rabbit mAb - 4276 from Cell Signaling Technology

Host Rabbit
Clonality Monoclonal
Clone D1G6

Phospho-CREB (Ser133) (1B6) Mouse mAb - 5180 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 1B6

Phospho-CREB (Ser133) (1B6) Mouse mAb - 5181 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 1B6

CREB Antibody - 9192 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

CREB-1 (D-12) - sc-377154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB-1 (D-12): sc-377154. Western blot analysis of CREB-1 expression in non-transfected: sc-117752 (A) and mouse CREB-1 transfected: sc-119446 (B) 293T whole cell lysates.

CREB-1 (X-12) - sc-240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB-1 (X-12): sc-240. Western blot analysis of CREB-1 expression in A-431 (A), A-673 (B) and Jurkat (C) nuclear extracts.

CREB-1 (H-74) - sc-25785 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB-1 (H-74): sc-25785. Western blot analysis of CREB-1 expression in A-431 (A) and A-673 (B) whole cell lysates.

CREB-1 (240) - sc-58 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB-1 (240) PE: sc-58 PE. Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: sc-3871.

CREB-1 (24H4B) - sc-271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB-1 (24H4B): sc-271. Western blot analysis of CREB-1 expression in Jurkat nuclear extract.

p-CREB-1 (Ser 133) - sc-7978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-CREB-1 (Ser 133): sc-7978. Western blot analysis of CREB-1 phosphorylation in non-transfected: sc-117752 (A) and mouse CREB-1 transfected: sc-119446 (B) 293T whole cell lysates.

p-CREB-1 (10E9) - sc-81486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
p-CREB-1 (10E9): sc-81486. Western blot analysis of p-CREB-1 expression in non-transfected: sc-110760 (A) and human CREB-1 transfected: sc-111160 (B) 293 whole cell lysates.

p-CREB-1 (Ser 129) - sc-101662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-CREB-1 (Ser 129): sc-101662. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining.

p-CREB-1 (Ser 133) - sc-101663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-CREB-1 (Ser 133): sc-101663. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining.
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