DHFR

Gene Symbol DHFR
Entrez Gene 1719
Alt Symbol DHFRP1, DYR
Species Human
Gene Type protein-coding
Description dihydrofolate reductase
Other Description -
Swissprots B4DDD2 P00374 Q6IRW8 Q14130
Accessions AAA58484 CAA25409 EAW95859 EAW95860 P00374 AA489055 AK293146 BAG56693 AK297302 BAG59770 AK308492 AK312642 BAG35526 BC000192 AAH00192 BC003584 AAH03584 BC009634 BC070280 AAH70280 BC071996 AAH71996 CB988944 DQ892816 ABM83742 DQ896062 ABM87061 EU145592 ABX57718 J00140 AAA58485 V00507 CAA23765 NM_000791 NP_000782 NM_001290354 NP_001277283 NM_001290357 NP_001277286 NR_110936
Function Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1. {ECO:0000269|PubMed:12096917, ECO:0000269|PubMed:21876188}.
Tissue Specificity Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain. {ECO:0000269|PubMed:21310276}.
Top Pathways Folate biosynthesis, One carbon pool by folate

DHFR (A-9) - sc-377091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHFR (A-9): sc-377091. Western blot analysis of DHFR expression in HeLa (A) and KNRK (B) whole cell lysates.

DHFR (C-4) - sc-393154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHFR (C-4): sc-393154. Western blot analysis of DHFR expression in HeLa (A), K-562 (B), A-431 (C), Jurkat (D) and Y79 (E) whole cell lysates.

DHFR (C-20) - sc-14780 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DHFR (C-20): sc-14780. Western blot analysis of DHFR expression in Hela whole cell lysate.

DHFR (A-4) - sc-74593 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHFR (A-4): sc-74593. Western blot analysis of human recombinant DHFR.

DHFR (E-18) - sc-14778 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DHFR (E-18): sc-14778. Western blot analysis of DHFR expression in HeLa (A), A-431 (B), Hep G2 (C), K-562 (D) and Jurkat (E) whole cell lysates.

DHFR (FL-187) - sc-33184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DHFR (FL-187): sc-33184. Western blot analysis of DHFR expression in HeLa whole cell lysate.

DHFR (F-8) - sc-74594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHFR (F-8): sc-74594. Western blot analysis of human recombinant DHFR.

DHFR (49) - sc-136246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DHFR (49): sc-136246. Western blot analysis of DHFR expression in RSV-3T3 whole cell lysate.

Anti-Dihydrofolate reductase (DHFR) antibody - ab82171 from Abcam

Prices $378.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed, paraffin-embedded section of Human breast carcinoma stained with ab82171 at 1/50 dilution. Incubate primary antibody (ab82171) for 30 minutes at RT.

Anti-Dihydrofolate reductase (DHFR) antibody - ab54612 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Dihydrofolate reductase (DHFR) antibody [3A11] - ab117984 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A11
All lanes : Anti-Dihydrofolate reductase (DHFR) antibody [3A11] (ab117984) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Dihydrofolate reductase (DHFR) cDNALysates/proteins at 5 µg per lane.

Anti-Dihydrofolate reductase (DHFR) antibody [EPR5284] - ab133546 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5284
All lanes : Anti-Dihydrofolate reductase (DHFR) antibody [EPR5284] (ab133546) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : U937 cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.

Anti-Dihydrofolate reductase (DHFR) antibody [EPR5285] - ab124814 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5285
All lanes : Anti-Dihydrofolate reductase (DHFR) antibody [EPR5285] (ab124814) at 1/10000 dilutionLane 1 : HeLa cell lysatesLane 2 : Jurkat cell lysatesLane 3 : Y-79 cell lysatesLane 4 : 293T cell lysatesLane 5 : Mouse spleen lysatesLane 6 : Rat kidney lysatesLysates/proteins at 10 µg per lane.

Anti-Dihydrofolate reductase (DHFR) antibody, prediluted - ab82166 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Formalin-fixed, paraffin-embedded section of Human breast carcinoma stained with Anti-DHFR antibody. Incubate primary antibody (ab82166) for 30 minutes at RT.

Anti-Dihydrofolate reductase (DHFR) antibody - C-terminal - ab135803 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Dihydrofolate reductase (DHFR) antibody - C-terminal (ab135803) at 1/50 dilution + Mouse liver tissue lysates at 35 µg

Anti-DHFR Antibody (aa1-187) - LS-C128641 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DHFR Antibody (Internal, clone EPR5284) - LS-C138829 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5284
Western blot analysis on (A) HeLa, (B) Jurkat, (C) U937, and (D) 293T cell lysates using anti-DHFR antibody.

Anti-DHFR Antibody (Internal) - LS-C210518 from LifeSpan Bioscience

Prices $360.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human Breast Carcinoma stained with anti-DHFR antibody

Anti-DHFR Antibody - LS-C192755 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using DHFR antibody.

Anti-DHFR Antibody (Internal, clone EPR5285) - LS-C138307 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5285
IHC of paraffin-embedded cervical carcinoma tissue using anti-DHFR antibody.

Anti-DHFR Antibody (aa135-164) - LS-C100566 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DHFR Antibody IHC of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DHFR Antibody - LS-C331576 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse lung using DHFR antibody at dilution of 1:100 (200x lens).

Anti-DHFR Antibody (clone 2B10) - LS-C197047 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B10
Immunofluorescence of monoclonal antibody to DHFR on HeLa cell. [antibody concentration 10 ug/ml]

Anti-DHFR Antibody (aa16-30) - LS-C344257 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded H. brain section using DHFR Antibody. Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

Anti-DHFR Antibody (clone 6G7) - LS-C114640 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G7
IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-DHFR mouse monoclonal antibody. (Dilution 1:50).
Search more