DHFR

Gene Symbol	DHFR
Entrez Gene	1719
Alt Symbol	DHFRP1, DYR
Species	Human
Gene Type	protein-coding
Description	dihydrofolate reductase
Other Description	-
Swissprots	B4DDD2 P00374 Q6IRW8 Q14130
Accessions	AAA58484 CAA25409 EAW95859 EAW95860 P00374 AA489055 AK293146 BAG56693 AK297302 BAG59770 AK308492 AK312642 BAG35526 BC000192 AAH00192 BC003584 AAH03584 BC009634 BC070280 AAH70280 BC071996 AAH71996 CB988944 DQ892816 ABM83742 DQ896062 ABM87061 EU145592 ABX57718 J00140 AAA58485 V00507 CAA23765 NM_000791 NP_000782 NM_001290354 NP_001277283 NM_001290357 NP_001277286 NR_110936
Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1. {ECO:0000269|PubMed:12096917, ECO:0000269|PubMed:21876188}.
Tissue Specificity	Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain. {ECO:0000269|PubMed:21310276}.
Top Pathways	Folate biosynthesis, One carbon pool by folate

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SimpleChIP ® Human DHFR Intron 1 Primers - 7531 from Cell Signaling Technology Category ChIP Kit Prices $102.00 Sizes 500 µl (250 PCR reactions)

Dihydrofolate reductase (DHFR), Human, ELISA Kit - E01D0284 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Dihydrofolate reductase, DHFR, Human, ELISA Kit - E9276h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 78-5000 pg/mL

Human DHFR(Dihydrofolate Reductase) ELISA Kit - E-EL-H5535 from Elabscience Category ELISA Kit Sensitivity 46.88 pg/mL Range 78.13—5000 pg/mL

DHFR, ELISA Kit - MBS2515698 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

Dihydrofolate Reductase (DHFR), ELISA Kit - MBS9312476 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25ng/ml-8ng/ml.

Chicken DHFR ELISA Kit (Custom ELISA) - LS-F20376 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Pig DHFR ELISA Kit (Custom ELISA) - LS-F20377 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Rat DHFR ELISA Kit (Custom ELISA) - LS-F20373 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Bovine DHFR ELISA Kit (Custom ELISA) - LS-F20374 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Mouse DHFR ELISA Kit (Sandwich ELISA) - LS-F20375 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

Human DHFR(Dihydrofolate Reductase) ELISA Kit - E-EL-H5535 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

Human Dihydrofolate reductase ELISA Kit - abx251829 from Abbexa Category ELISA Kit Sensitivity 46.875 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Human DHFR ELISA Kit (Sandwich ELISA) - LS-F13155 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

Human Dihydrofolate reductase ELISA Kit - EKE54708 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 34 pg/mL Range 78-5000 pg/mL

DHFR - EKH4926 from Nordic BioSite Sensitivity 46.875pg/ml Range 78.125--5000pg/ml

DHFR ELISA Kit (Human) : 96 Wells (OKEH01940) - OKEH01940 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 34 pg/mL Range 78 - 5000 pg/mL

Dihydrofolate reductase (DHFR) (Human) ELISA Kit - E4301 from Biovision Category ELISA Kit Prices $695.00 Sizes 100 assays

Human DHFR ELISA Kit - E011922 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

Human Dihydrofolate reductase ELISA Kit - EK4942 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Range 0.312-20 ng/mL

anti-DHFR antibody [5B2] - ARG57150 from Arigo Biolaboratories Category ELISA Kit

anti-DHFR antibody - ARG52947 from Arigo Biolaboratories Category ELISA Kit

anti-DHFR antibody (Ready-to-Use) - ARG52948 from Arigo Biolaboratories Category ELISA Kit

Human Dihydrofolate reductase (DHFR) ELISA Kit - AE47326HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t

Dihydrofolate reductase, ELISA Kit - MBS9428768 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Sensitivity Less than 34pg/mL Range 78-5000 pg/mL

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