POLD1

Gene Symbol	POLD1
Entrez Gene	5424
Alt Symbol	CDC2, CRCS10, MDPL, POLD
Species	Human
Gene Type	protein-coding
Description	polymerase (DNA directed), delta 1, catalytic subunit
Other Description	CDC2 homolog|DNA polymerase delta catalytic subunit|DNA polymerase subunit delta p125|polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Swissprots	Q96H98 P28340 Q8NER3
Accessions	AAM76971 EAW71856 EAW71857 P28340 AA236879 AB209560 BAD92797 BC008800 AAH08800 BM193218 CD101690 DQ234348 ABB29977 DQ895953 ABM86879 EU176381 ABW03832 M80397 AAA58439 M81735 AAA35768 XM_005259008 XP_005259065 XM_011527038 XP_011525340 XM_011527039 XP_011525341 XR_935835 NM_001256849 NP_001243778 NM_001308632 NP_001295561 NM_002691 NP_002682 NR_046402
Function	Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.
Subcellular Location	Nucleus.
Tissue Specificity	Expressed across a panel of tissues, with high levels of expression in heart and lung. {ECO:0000269|PubMed:23770608}.
Top Pathways	HTLV-I infection, Nucleotide excision repair, Base excision repair, Homologous recombination, Mismatch repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cyclin Dependent Kinase 1 (CDK1), Human, ELISA Kit - SEB888Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

polymerase (DNA directed) , delta 1, catalytic subunit 125kDa, ELISA Kit - MBS9336676 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polymerase DNA Directed Delta 1 (POLd), ELISA Kit - MBS2024865 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.054ng/mL. Range 0.156-10ng/mL

ELISA Kit for Polymerase DNA Directed Delta 1 (POLd) - SEC717Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Cyclin Dependent Kinase 1 (CDK1) - SEB888Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.068ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Polymerase DNA Directed Delta 1 (POLd) - SEC717Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Cyclin Dependent Kinase 1 (CDK1), Human, ELISA Kit - DL-CDK1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human POLD1 ELISA Kit (Sandwich ELISA) - LS-F25387 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

CDC2 ELISA Kit - DEIA-XYA370 from Creative Diagnostics Category ELISA Kit

CDC2 (Phospho-Thr161) ELISA Kit - DEIA-XYA371 from Creative Diagnostics Category ELISA Kit

CDC2 (Phospho-Tyr15) ELISA Kit - DEIA-XYA372 from Creative Diagnostics Category ELISA Kit

Human POLD1 ELISA Kit - E030091 from Biobool Category ELISA Kit

Human POLd ELISA Kit - E030134 from Biobool Category ELISA Kit Sensitivity Typically less than 0.054ng/mL.

POLD1 ELISA Kit (Human) (OKCD00347) - OKCD00347 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.054 ng/mL Range 0.156-10 ng/mL

anti-PolD1 antibody - ARG56297 from Arigo Biolaboratories Category ELISA Kit

CDC2 Colorimetric Cell-Based ELISA Kit - EKA50109 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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