POLD1

Gene Symbol	POLD1
Entrez Gene	5424
Alt Symbol	CDC2, CRCS10, MDPL, POLD
Species	Human
Gene Type	protein-coding
Description	polymerase (DNA directed), delta 1, catalytic subunit
Other Description	CDC2 homolog|DNA polymerase delta catalytic subunit|DNA polymerase subunit delta p125|polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Swissprots	Q96H98 P28340 Q8NER3
Accessions	AAM76971 EAW71856 EAW71857 P28340 AA236879 AB209560 BAD92797 BC008800 AAH08800 BM193218 CD101690 DQ234348 ABB29977 DQ895953 ABM86879 EU176381 ABW03832 M80397 AAA58439 M81735 AAA35768 XM_005259008 XP_005259065 XM_011527038 XP_011525340 XM_011527039 XP_011525341 XR_935835 NM_001256849 NP_001243778 NM_001308632 NP_001295561 NM_002691 NP_002682 NR_046402
Function	Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.
Subcellular Location	Nucleus.
Tissue Specificity	Expressed across a panel of tissues, with high levels of expression in heart and lung. {ECO:0000269|PubMed:23770608}.
Top Pathways	HTLV-I infection, Nucleotide excision repair, Base excision repair, Homologous recombination, Mismatch repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DNA Polymerase delta, catalytic subunit full length protein - ab132036 from Abcam Category Protein Source Wheat germ Species Human

CDC2 / CDK2 Antibody Blocking Peptide - LS-E3956 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E10491 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E10566 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E25165 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E7438 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E7262 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC2 / CDK2 Antibody Blocking Peptide - LS-E9021 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLD1 Antibody Blocking Peptide - LS-E7164 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DNA Polymerase delta, catalytic subunit Recombinant Protein - H00005424-P01 from Novus Biologicals Category Protein

Recombinant Human Cdc2/Cyclin E Protein - P4641 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Source Insect Species Human

Recombinant Human Cdc2/Cyclin B1 Protein - P4640 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Source Insect Species Human

Recombinant Human Cdc2/Cyclin A2 Protein - P4639 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Source Insect Species Human

POLD1-Antibody-Center-Blocking-Peptide - BP2867c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cdc2 peptide - GTX28008 from GeneTex Category Peptide Prices $179.00 Sizes 100 μg

Cdk2 peptide - GTX28009 from GeneTex Category Peptide Prices $179.00 Sizes 100 μg Species Human

CDC2 Blocking Peptide - 33R-8578 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC2 Blocking Peptide - 33R-1643 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC2 Blocking Peptide - 33R-2241 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC2 Blocking Peptide - 33R-2335 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC2 Blocking Peptide - 33R-4500 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDK1 protein (His tag) - 80R-4146 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

CDK1 protein (His tag) - 80R-4012 from Fitzgerald Category Protein Prices $375.00 Sizes 50 µg Source Insect cells

CDC2 (phospho-Thr161) Blocking Peptide - abx062383 from Abbexa Category Peptide Species Human, Bovine, Chicken, Monkey, Zebrafish

CDC2 (phospho-Tyr15) Blocking Peptide - abx062058 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

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