POLD1

Gene Symbol POLD1
Entrez Gene 5424
Alt Symbol CDC2, CRCS10, MDPL, POLD
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), delta 1, catalytic subunit
Other Description CDC2 homolog|DNA polymerase delta catalytic subunit|DNA polymerase subunit delta p125|polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Swissprots Q96H98 P28340 Q8NER3
Accessions AAM76971 EAW71856 EAW71857 P28340 AA236879 AB209560 BAD92797 BC008800 AAH08800 BM193218 CD101690 DQ234348 ABB29977 DQ895953 ABM86879 EU176381 ABW03832 M80397 AAA58439 M81735 AAA35768 XM_005259008 XP_005259065 XM_011527038 XP_011525340 XM_011527039 XP_011525341 XR_935835 NM_001256849 NP_001243778 NM_001308632 NP_001295561 NM_002691 NP_002682 NR_046402
Function Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.
Subcellular Location Nucleus.
Tissue Specificity Expressed across a panel of tissues, with high levels of expression in heart and lung. {ECO:0000269|PubMed:23770608}.
Top Pathways HTLV-I infection, Nucleotide excision repair, Base excision repair, Homologous recombination, Mismatch repair

POLD1 - MBS1273021 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC008800

Human POLD1 ORF Clone (BC008800) - CDCS410130 from Creative biogene

Species Human
Accession P28340
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