Izumo1

Gene Symbol	Izumo1
Entrez Gene	73456
Alt Symbol	1700058F15Rik, Izumo
Species	Mouse
Gene Type	protein-coding
Description	izumo sperm-egg fusion 1
Other Description	OBF|izumo sperm-egg fusion protein 1|oocyte binding/fusion factor|sperm-specific protein Izumo
Swissprots	Q9D9J7
Accessions	EDL22878 Q9D9J7 AB195681 BAD91011 AK006830 BAB24761 BC139270 BC152920 AAI52921 XM_006541222 XP_006541285 NM_001018013 NP_001018013
Function	Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. {ECO:0000269|PubMed:15759005, ECO:0000269|PubMed:24739963}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. {ECO:0000269|PubMed:15759005, ECO:0000269|PubMed:19658160}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Mouse Izumo sperm-egg fusion protein 1(Izumo1) - CSB-YP863556MO CSB-EP863556MO CSB-BP863556MO CSB-MP863556MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse IZUMO1 Protein - IZUMO1-8402M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Izumo sperm-egg fusion protein 1 (Izumo1), Recombinant Protein - MBS1380107 from MyBioSource Category Protein Prices $1,055.00, $1,055.00, $1,285.00, $1,285.00, $1,645.00, $1,645.00, $2,110.00, $2,110.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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