DYNC1I1

Gene Symbol	DYNC1I1
Entrez Gene	1780
Alt Symbol	DNCI1, DNCIC1
Species	Human
Gene Type	protein-coding
Description	dynein, cytoplasmic 1, intermediate chain 1
Other Description	DH IC-1\|cytoplasmic dynein 1 intermediate chain 1\|cytoplasmic dynein intermediate chain 1\|dynein intermediate chain 1, cytosolic\|dynein, cytoplasmic, intermediate polypeptide 1
Swissprots	G5E9K1 Q8TBF7 F5H050 O14576 B4DME3 Q9Y2X1
Accessions	AAB67047 AAB70113 AAS01994 AAS07455 EAL24126 EAW76751 EAW76752 EAW76753 EAW76754 EAW76755 O14576 AF063228 AAC33443 AF123074 AAD26852 AK091339 BAC03639 AK297427 BAG59855 AK309419 AK313148 BAG35966 BC012504 BC022540 AAH22540 BC032945 AAH32945 BC037854 AAH37854 BC053542 AAH53542 BP307571 DA491512 DB343806 XM_011515861 XP_011514163 XM_011515862 XP_011514164 XM_011515863 XP_011514165 XM_011515864 XP_011514166 NM_001135556 NP_001129028 NM_001135557 NP_001129029 NM_001278421 NP_001265350 NM_001278422 NP_001265351 NM_004411 NP_004402
Function	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Subcellular Location	Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000269\|PubMed:19229290}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269\|PubMed:19229290}.
Top Pathways	Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection

Dynein IC1, cytosolic (S-20) - sc-32191 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dynein IC1, cytosolic (S-20): sc-32191. Western blot analysis of Dynein IC1, cytosolic expression in rat (A) and mouse (B) brain tissue extracts.

Dynein IC1, cytosolic (D-16) - sc-32192 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dynein IC1/2, cytosolic (2Q46) - sc-70997 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Dynein IC1/2, cytosolic (2Q46): sc-70997. Western blot analysis of Dynein IC1/2, cytosolic expression in T98G (A), U-87 MG (B), IMR-32 (C) and L8 (D) whole cell lysates and rat brain (E) and mouse brain (F) tissue extracts.

Anti-Dynein axonemal intermediate chain 1 antibody - ab81507 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Dynein axonemal intermediate chain 1 antibody (ab81507) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Dynein axonemal intermediate chain 1 antibody [EPR11222-78] - ab169758 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR11222-78

All lanes : Anti-Dynein axonemal intermediate chain 1 antibody [EPR11222-78] (ab169758) at 1/1000 dilutionLane 1 : Human Fetal brain lysateLane 2 : Human hypothalamus lysateLysates/proteins at 10 µg per lane.

Anti-DYNC1I1 Antibody (aa110-159) - LS-C81695 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-DYNC1I1 Antibody (aa21-70) - LS-C81694 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DNCIC1 Antibody (74.1) - NB300-726 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	74.1

Western Blot: DNCIC1 Antibody (74.1) [NB300-726] - Analysis of cytoplasmic dynein in HeLa cell lysate.

DNCIC1 Antibody (70.1) - NB600-410 from Novus Biologicals

Prices	$369.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	70.1

DNCIC1 Antibody - NBP2-16202 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNCIC1 Antibody [NBP2-16202] - Sample (30 ug of whole cell lysate) A: Raji B: K562 C: HL-60 7. 5% SDS PAGE gel, diluted at 1:1000.

DNCIC1 Antibody - NBP2-16201 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNCIC1 Antibody [NBP2-16201] - Sample (30 ug of whole cell lysate) A: Jurkat B: NCI-H929 7. 5% SDS PAGE gel, diluted at 1:3000.

DNCIC1 Antibody - NBP2-38933 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: DNCIC1 Antibody [NBP2-38933] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells, cells in molecular layer and cells in granular layer.

DNCIC1 Antibody - NBP1-32659 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNCIC1 Antibody [NBP1-32659] - (30 ug of whole cell lysate) A: Molt-4 7.5 % SDS PAGE diluted at 1:1000

DYNC1I1 Polyclonal Antibody - bs-10470R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

$Mouse splenocytes probed with Rabbit Anti-DYNC1I1 Polyclonal Antibody, FITC Conjugated (bs-10470R-FITC) at 1:100 for 40 minutes (green)compared to control cells (blue).\\n$

DYNC1I1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10470R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10470R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10470R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-10470R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, Cy3 Conjugated - bs-10470R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, Cy5 Conjugated - bs-10470R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, Cy5.5 Conjugated - bs-10470R-Cy5.5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, Cy7 Conjugated - bs-10470R-Cy7 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, FITC Conjugated - bs-10470R-FITC from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

$Mouse splenocytes probed with Rabbit Anti-DYNC1I1 Polyclonal Antibody, FITC Conjugated (bs-10470R-FITC) at 1:100 for 40 minutes (green)compared to control cells (blue).\\n$

DYNC1I1 Polyclonal Antibody, Biotin Conjugated - bs-10470R-Biotin from Bioss

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1I1 Polyclonal Antibody, HRP Conjugated - bs-10470R-HRP from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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