DYNC1I1

Gene Symbol	DYNC1I1
Entrez Gene	1780
Alt Symbol	DNCI1, DNCIC1
Species	Human
Gene Type	protein-coding
Description	dynein, cytoplasmic 1, intermediate chain 1
Other Description	DH IC-1|cytoplasmic dynein 1 intermediate chain 1|cytoplasmic dynein intermediate chain 1|dynein intermediate chain 1, cytosolic|dynein, cytoplasmic, intermediate polypeptide 1
Swissprots	G5E9K1 Q8TBF7 F5H050 O14576 B4DME3 Q9Y2X1
Accessions	AAB67047 AAB70113 AAS01994 AAS07455 EAL24126 EAW76751 EAW76752 EAW76753 EAW76754 EAW76755 O14576 AF063228 AAC33443 AF123074 AAD26852 AK091339 BAC03639 AK297427 BAG59855 AK309419 AK313148 BAG35966 BC012504 BC022540 AAH22540 BC032945 AAH32945 BC037854 AAH37854 BC053542 AAH53542 BP307571 DA491512 DB343806 XM_011515861 XP_011514163 XM_011515862 XP_011514164 XM_011515863 XP_011514165 XM_011515864 XP_011514166 NM_001135556 NP_001129028 NM_001135557 NP_001129029 NM_001278421 NP_001265350 NM_001278422 NP_001265351 NM_004411 NP_004402
Function	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Subcellular Location	Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19229290}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:19229290}.
Top Pathways	Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dynein axonemal intermediate chain 1 full length protein - ab158299 from Abcam Category Protein Source Wheat germ Species Human

DYNC1I1 Antibody Blocking Peptide - LS-E18679 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DYNC1I1 Antibody Blocking Peptide - LS-E18680 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DNCIC1 Protein - H00001780-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DYNC1I1 Blocking Peptide - 33R-3577 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DYNC1I1 Blocking Peptide - 33R-4130 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DYNC1I1 - H00001780-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DYNC1I1 - H00001780-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DYNC1I1 fusion protein - ag5049 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

DYNC1I1 fusion protein - ag4810 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Cytoplasmic dynein 1 intermediate chain 1(DYNC1I1) - CSB-YP007293HU CSB-EP007293HU CSB-BP007293HU CSB-MP007293HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DYNC1I1 (transcript variant 1) - TP317108 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DNCIC1 Protein - NBP2-38933PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

DYNC1I1-Antibody-C-term-Blocking-Peptide - BP9232b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DYNC1I1 Peptide, Human - M34GP04641H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1), Recombinant Protein - MBS1225159 from MyBioSource Category Protein Prices $1,445.00, $1,445.00, $1,670.00, $1,670.00, $2,450.00, $2,450.00, $2,890.00, $2,890.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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