DYNC1I1

Gene Symbol DYNC1I1
Entrez Gene 1780
Alt Symbol DNCI1, DNCIC1
Species Human
Gene Type protein-coding
Description dynein, cytoplasmic 1, intermediate chain 1
Other Description DH IC-1|cytoplasmic dynein 1 intermediate chain 1|cytoplasmic dynein intermediate chain 1|dynein intermediate chain 1, cytosolic|dynein, cytoplasmic, intermediate polypeptide 1
Swissprots G5E9K1 Q8TBF7 F5H050 O14576 B4DME3 Q9Y2X1
Accessions AAB67047 AAB70113 AAS01994 AAS07455 EAL24126 EAW76751 EAW76752 EAW76753 EAW76754 EAW76755 O14576 AF063228 AAC33443 AF123074 AAD26852 AK091339 BAC03639 AK297427 BAG59855 AK309419 AK313148 BAG35966 BC012504 BC022540 AAH22540 BC032945 AAH32945 BC037854 AAH37854 BC053542 AAH53542 BP307571 DA491512 DB343806 XM_011515861 XP_011514163 XM_011515862 XP_011514164 XM_011515863 XP_011514165 XM_011515864 XP_011514166 NM_001135556 NP_001129028 NM_001135557 NP_001129029 NM_001278421 NP_001265350 NM_001278422 NP_001265351 NM_004411 NP_004402
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Subcellular Location Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19229290}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:19229290}.
Top Pathways Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection

DYNC1I1-Over-expression-Lysate - LY10950a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag DYNC1I1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DYNC1I1 gene

DNCIC1 Overexpression Lysate (Native) - NBP2-10591 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: DNCIC1 Overexpression Lysate (Adult Normal) [NBP2-10591] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DNCIC1.

Panoply™ Human DYNC1I1 Knockdown Stable Cell Line - CSC-DC004641 from Creative biogene

Category Cell Line
Species Human
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