DVL2

Gene Symbol DVL2
Entrez Gene 1856
Alt Symbol -
Species Human
Gene Type protein-coding
Description dishevelled segment polarity protein 2
Other Description dishevelled 2 (homologous to Drosophila dsh)|dishevelled, dsh homolog 2|segment polarity protein dishevelled homolog DVL-2
Swissprots Q53XM0 O14641 D3DTN3
Accessions EAW90244 EAW90245 O14641 AF006012 AAB65243 AK026019 AK297099 BAG59612 AK297285 BAG59756 AK304229 BAG65098 AK309771 AK312829 BC014844 AAH14844 BG716400 BT009822 AAP88824 CB994349 JF432818 ADZ16035 XM_005256502 XP_005256559 XM_006721469 XP_006721532 NM_004422 NP_004413
Function Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). {ECO:0000250}.
Top Pathways Wnt signaling pathway, Notch signaling pathway, Basal cell carcinoma, Melanogenesis, HTLV-I infection

Human-DVL2-cDNA-Clone - DC03939 from Abgent, a WuXi AppTec company

Prices $993.60
Sizes 10 µg
Species Human
Accession BC014844

DVL2 - MBS1273741 from MyBioSource

Species Human
Accession BC014844

Human DVL2 cDNA clone(NM_004422.2) - CDFH005515 from Creative Biomart

Species Human
Accession NM_004422.2

Human DVL2 ORF Clone(NM_004422.2) - CDCL161680 from Creative Biomart

Species Human
Accession NM_004422.2

Human DVL2 ORF Clone(NM_004422.2) - CDCR287972 from Creative Biomart

Species Human
Accession NM_004422.2

Human DVL2 ORF Clone(NM_004422.2) - CDCR287973 from Creative Biomart

Species Human
Accession NM_004422.2

Human DVL2 ORF Clone(NM_004422.2) - CDCR287972 from Creative biogene

Species Human

Human DVL2 ORF Clone (BC014844) - CDCS411768 from Creative biogene

Species Human
Accession O14641

Human DVL2 cDNA Clone(NM_004422.2) - CDFH005515 from Creative biogene

Species Human
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