DVL2

Gene Symbol	DVL2
Entrez Gene	1856
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	dishevelled segment polarity protein 2
Other Description	dishevelled 2 (homologous to Drosophila dsh)|dishevelled, dsh homolog 2|segment polarity protein dishevelled homolog DVL-2
Swissprots	Q53XM0 O14641 D3DTN3
Accessions	EAW90244 EAW90245 O14641 AF006012 AAB65243 AK026019 AK297099 BAG59612 AK297285 BAG59756 AK304229 BAG65098 AK309771 AK312829 BC014844 AAH14844 BG716400 BT009822 AAP88824 CB994349 JF432818 ADZ16035 XM_005256502 XP_005256559 XM_006721469 XP_006721532 NM_004422 NP_004413
Function	Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). {ECO:0000250}.
Top Pathways	Wnt signaling pathway, Notch signaling pathway, Basal cell carcinoma, Melanogenesis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Dishevelled 2 peptide - ab173138 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Dishevelled 2 full length protein - ab152348 from Abcam Category Protein Source Wheat germ Species Human

DVL2 / Dishevelled 2 Antibody Blocking Peptide - LS-E3696 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DVL2 / Dishevelled 2 Antibody Blocking Peptide - LS-E11220 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DVL2 / Dishevelled 2 Antibody Blocking Peptide - LS-E11219 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Dishevelled-2 Protein - H00001856-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DVL2-Antibody-C-term-Blocking-Peptide - BP14900b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DVL2 Blocking Peptide - 33R-1228 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human DVL2 Protein - abx066349 from Abbexa Category Protein Source E.coli Species Human

Dishevelled-2 / DVL2 - H00001856-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Dishevelled-2 / DVL2 - H00001856-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DVL2 fusion protein - ag2666 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human DVL2, GST-tagged - DVL2-107H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human DVL2, GST-tagged - DVL2-108H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Dishevelled, Dsh Homolog 2 (DVL2) - RPL454Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Dishevelled, Dsh Homolog 2 (DVL2) - RPL454Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Segment polarity protein dishevelled homolog DVL-2(DVL2) - CSB-YP007286HU CSB-EP007286HU CSB-BP007286HU CSB-MP007286HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Dishevelled, Dsh Homolog 2 (DVL2) - RPU141211 from Biomatik Category Protein Prices $231.00, $462.00, $693.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

DVL2 Peptide - abx164709 from Abbexa Category Peptide Species Human, Mouse, Rat

Dishevelled-2 Recombinant Protein Antigen - NBP1-87550PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DVL2 Peptide, Human - M34GP04635H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Dishevelled, Dsh Homolog 2 (DVL2) - RPU41211 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DVL2 Recombinant Protein (OPCD02822) - OPCD02822 from Aviva Systems Biology Category Protein Source E.coli Species Human

Dishevelled-2 Recombinant Protein Antigen - NBP2-56345PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Dishevelled, Dsh Homolog 2 (DVL2), Recombinant Protein - MBS2018666 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Search more