Gene Symbol | Tnfsf12 |
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Entrez Gene | 21944 |
Alt Symbol | Apo3l, Dr3l, Dr3lg, Tweak |
Species | Mouse |
Gene Type | protein-coding |
Description | tumor necrosis factor (ligand) superfamily, member 12 |
Other Description | TNF-related weak inducer of apoptosis|tumor necrosis factor ligand superfamily member 12 |
Swissprots | O54907 Q9CTP2 |
Accessions | CAI51948 O54907 AF030100 AAC53517 AK020909 BAB32249 AK170297 BAE41696 AK171014 BAE42185 BC152795 AAI52796 BX634398 CB204861 CB848966 NM_011614 NP_035744 |
Function | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. |
Top Pathways | Cytokine-cytokine receptor interaction |
TWEAK (MTW-1) - sc-56251 from Santa Cruz Biotechnology
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Anti-TWEAK antibody [MTW-1] (Biotin) - ab95626 from Abcam
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Anti-TWEAK antibody [MTW-1] (Phycoerythrin) - ab93571 from Abcam
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TWEAK/TNFSF12 Antibody - AF1237 from Novus Biologicals
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TWEAK/TNFSF12 Antibody [Biotin] - BAF1237 from Novus Biologicals
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TWEAK/TNFSF12 Antibody (MTW-1) [Biotin] - NBP1-43476 from Novus Biologicals
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Tnfsf12 Antibody (OASA05786) - OASA05786 from Aviva Systems Biology
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TWEAK antibody (biotin) - 61R-1674 from Fitzgerald
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TNF12 antibody - 70R-33707 from Fitzgerald
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TNFSF12 Antibody - abx116357 from Abbexa
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Rat Anti-Mouse TWEAK - 129-10663 from RayBiotech
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LEAF™ Purified anti-mouse CD255 (TWEAK) Antibody - 120008 from Biolegend
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PE anti-mouse CD255 (TWEAK) Antibody - 120005 from Biolegend
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TWEAK, Monoclonal Antibody - MBS219446 from MyBioSource
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TWEAK - MBS832238 from MyBioSource
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TWEAK - MBS833317 from MyBioSource
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Mouse TWEAK Antibody - GWB-4D5913 from Genway Biotech
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Anti-TNFSF12 monoclonal antibody, clone MTW-1 - CABT-47858RM from Creative Diagnostics
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Rat anti-TWEAK Monoclonal antibody [clone NUX-2], PE-Conjugated - DCABH-10299 from Creative Diagnostics
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Rat anti-TWEAK Monoclonal antibody [clone NUX-2], Biotin-Conjugated - DCABH-10345 from Creative Diagnostics
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TWEAK Antibody | MTW-1 - MCA4712GA from AbD Serotec
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Anti-Mouse CD255 (TWEAK) Biotin (To be Discontinued) - 13-9913 from eBioscience
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TNFSF12 Antibody - CSB-PA023987GA01HU from Cusabio
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Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 12 (TNFSF12) - PAD933Mu01 from Cloud-clone
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Tumor Necrosis Factor Ligand Superfamily, Polyclonal Antibody - MBS2026932 from MyBioSource
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