Fos

Gene Symbol Fos
Entrez Gene 14281
Alt Symbol D12Rfj1, c-fos, cFos
Species Mouse
Gene Type protein-coding
Description FBJ osteosarcoma oncogene
Other Description cellular oncogene fos|proto-oncogene c-Fos|proto-oncogene protein c-fos
Swissprots P01101
Accessions AAA96699 CAA24105 EDL02869 EDL02870 EDL02871 P01101 AK154418 BAE32571 AK159688 AY423854 AAR00345 BC013242 BC029814 AAH29814 NM_010234 NP_034364
Function Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta- mediated signaling (By similarity). Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. {ECO:0000250, ECO:0000269|PubMed:12134156, ECO:0000269|PubMed:12972619, ECO:0000269|PubMed:15719069, ECO:0000269|PubMed:21998197, ECO:0000269|PubMed:22105363}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity). {ECO:0000250}.
Top Pathways Toll-like receptor signaling pathway, cAMP signaling pathway, Circadian entrainment, TNF signaling pathway, Prolactin signaling pathway

FOS antibody - 70R-34384 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FOS antibody - 70R-31287 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FOS antibody (Thr32) - 70R-32766 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FOS antibody (Thr232) - 70R-34397 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Fos antibody - 70R-34513 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Fos antibody - 70R-31126 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FOS antibody (Ser362) - 70R-31286 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FOS antibody - 70R-34398 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

c-fos antibody - SP5302P from Acris Antibodies

Prices $310.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal
Figure 1. Western blot of cFos on NIH 3T3 cell lysate using SP5302P. Lane 1 shows non-immune serum and lane 2 shows immune serum.

Anti-FOS (aa 1-100) polyclonal antibody - DPABH-27324 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

c-Fos Polyclonal Antibody - OSC00040W from Thermo Fisher Scientific

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c-Fos (mouse) polyclonal antibody - ALX-210-113-C200 from Enzo Life Sciences

Prices $399.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

FOS (N) Antibody, Rabbit Polyclonal - R0701-1 from Abiocode

Prices $219.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
FOS Antibody Western (Abiocode)

cFOS antibody - 70R-49757 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

anti-c-Fos antibody - ARG65613 from Arigo Biolaboratories

ARG65613 anti-c-Fos antibody WB image Western Blot: 40 μg of HeLa cells lysates stained with ARG65613 anti-c-Fos antibody at 1/400 dilution. Exposure time: 15 seconds.

c-Fos (phospho-Thr232) antibody (FITC) - orb8704 from Biorbyt

Host Rabbit
Clonality Polyclonal
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