Fos

Gene Symbol	Fos
Entrez Gene	14281
Alt Symbol	D12Rfj1, c-fos, cFos
Species	Mouse
Gene Type	protein-coding
Description	FBJ osteosarcoma oncogene
Other Description	cellular oncogene fos|proto-oncogene c-Fos|proto-oncogene protein c-fos
Swissprots	P01101
Accessions	AAA96699 CAA24105 EDL02869 EDL02870 EDL02871 P01101 AK154418 BAE32571 AK159688 AY423854 AAR00345 BC013242 BC029814 AAH29814 NM_010234 NP_034364
Function	Nuclear phosphoprotein which forms a tight but non- covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta- mediated signaling (By similarity). Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. {ECO:0000250, ECO:0000269|PubMed:12134156, ECO:0000269|PubMed:12972619, ECO:0000269|PubMed:15719069, ECO:0000269|PubMed:21998197, ECO:0000269|PubMed:22105363}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity). {ECO:0000250}.
Top Pathways	Toll-like receptor signaling pathway, cAMP signaling pathway, Circadian entrainment, TNF signaling pathway, Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C-Fos, Mouse, ELISA Kit - E03C0735 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/mL,

C-Fos, Mouse, ELISA Kit - YHB0276Mo from ARP American Research Products Category ELISA Kit

Proto-oncogene c-Fos, Fos, Mouse, ELISA Kit - E1291m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS), Mouse, ELISA Kit - SEB291Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Mouse FOS ELISA Kit - MF0120 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse c-Fos ELISA Kit - MC0742 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse FOS(V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog) ELISA Kit - E-EL-M1235 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Mouse FOS (V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog) CLIA Kit - E-CL-M0683 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

v-fos FBJ murine osteosarcoma viral oncogene homolog, ELISA Kit - MBS703222 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.2 pg/ml Range 4.6 pg/ml-300 pg/ml

Mouse c-fos ELISA Kit - CSB-E11889m from Cusabio Category ELISA Kit Sensitivity 7.8 pg/ml Range 31.25 pg/ml-2000 pg/ml

Mouse c-Fos ELISA - E03C0735 from BlueGene Biotech Category ELISA Kit

Mouse V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog ELISA - E03F0113 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS) - SEB291Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse FOS(V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog) ELISA Kit - E-EL-M1235 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Mouse c-fos ELISA Kit - abx051283 from Abbexa Category ELISA Kit Sensitivity 8 pg/ml Range 33 pg/ml - 2000 pg/ml

Mouse FOS ELISA Kit - abx154033 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

V-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog (FOS), Mouse, ELISA Kit - DL-FOS-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

Mouse FOS ELISA Kit - orb365921 from Biorbyt Category ELISA Kit Prices $544.00, $612.00 Sizes 48 test, 96 test Range Detection Range: 0.156-10ng/mL Detection low threshold: 0.063ng/mL

Mouse FOS ELISA Kit - abx570270 from Abbexa Category ELISA Kit Sensitivity 0.063 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse c-fos ELISA Kit - EKC36534 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 1.2 pg/ml Range 4.6 pg/ml-300 pg/ml

Mouse Proto-oncogene c-Fos ELISA Kit - EKE53234 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

FOS - EKM1148 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

FOS ELISA Kit (Mouse) : 96 Wells (OKEH00925) - OKEH00925 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.078 ng/mL Range 0.31 - 20 ng/mL

Mouse c-Fos ELISA Kit - E046275 from Biobool Category ELISA Kit

Mouse Fos ELISA Kit - E053394 from Biobool Category ELISA Kit Sensitivity 0.094ng/mL

Search more