Ncstn

Gene Symbol	Ncstn
Entrez Gene	289231
Alt Symbol	-
Species	Rat
Gene Type	protein-coding
Description	nicastrin
Other Description	-
Swissprots	Q8CGU6 Q8CH12
Accessions	EDL94675 EDL94676 Q8CGU6 AF510722 AAO15915 AY101378 AAM44078 BC074006 BC167747 AAI67747 FQ212793 XM_006250283 XP_006250345 XM_008769733 XP_008767955 XM_008769734 XP_008767956 XM_008769735 XP_008767957 NM_001034026 NM_001034027 NM_174864 NP_777353
Function	Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Melanosome {ECO:0000250}.
Top Pathways	Notch signaling pathway, Alzheimer's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat NCSTN Gene cDNA Clone - orb172708 from Biorbyt Prices $264.00 Sizes 10 μg Species Rat

Rat Ncstn cDAN Clone(NM_174864.3) - CDFR014832 from Creative Biomart Species Rat Accession NM_174864.3

Rat Ncstn ORF Clone(NM_174864.3) - CDCR381749 from Creative Biomart Species Rat Accession NM_174864.3

Rat Nicastrin/NCSTN Gene ORF cDNA clone in cloning vector - RG81043-U from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, N-His tag - RG81043-NH from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - RG81043-ACR from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, C-HA tag - RG81043-CY from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, C-Flag tag - RG81043-CF from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, N-HA tag - RG81043-NY from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, N-Flag tag - RG81043-NF from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid - RG81043-UT from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, C-His tag - RG81043-CH from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - RG81043-ACG from Sino Biological Species Rat

Rat Nicastrin/NCSTN Gene ORF cDNA clone expression plasmid, N-Myc tag - RG81043-NM from Sino Biological Species Rat

Rat NCSTN Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - RG81043-CM from Sino Biological Species Rat Accession NM_174864.3

Rat Ncstn ORF Clone(NM_174864.3) - CDCR381749 from Creative biogene Species Rat

Rat Ncstn cDNA Clone(NM_174864.3) - CDFR014832 from Creative biogene Species Rat

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