PLA2G5

Gene Symbol PLA2G5
Entrez Gene 5322
Alt Symbol FRFB, GV-PLA2, PLA2-10, hVPLA(2)
Species Human
Gene Type protein-coding
Description phospholipase A2, group V
Other Description Ca2+-dependent phospholipase A2|calcium-dependent phospholipase A2|phosphatidylcholine 2-acylhydrolase 5
Swissprots Q8N435 P39877
Accessions AAR92480 EAW94911 EAW94912 EAW94913 P39877 AK097693 BAG53516 AV709457 BC036792 AAH36792 BM684907 BM705479 BX648966 U03090 AAC28886 XM_005245891 XP_005245948 XM_005245892 XP_005245949 XM_005245893 XP_005245950 XM_006710696 XP_006710759 XM_011541584 XP_011539886 XM_011541585 XP_011539887 XM_011541586 XP_011539888 XM_011541587 XP_011539889 XM_011541588 XP_011539890 XM_011541589 XP_011539891 XM_011541590 XP_011539892 XM_011541591 XP_011539893 XM_011541592 XP_011539894 NM_000929 NP_000920
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
Subcellular Location Secreted.
Tissue Specificity Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level). {ECO:0000269|PubMed:22137173}.
Top Pathways Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism

group V PLA 2 (1B7) - sc-20023 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
group V PLA<sub>2</sub> (1B7): sc-20023. Immunofluorescence staining of methanol-fixed A-10 cells showing cytoplasmic staining.

group V PLA 2 (M-137) - sc-135019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
group V PLA<sub>2</sub> (M-137): sc-135019. Western blot analysis of group V PLA<sub>2</sub> expression in A10 (A) and NIH/3T3 (B) whole cell lysates and mouse thymus tissue extract (C).

group V PLA 2 (2A5) - sc-20024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

group V PLA 2 (3G1) - sc-18828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
group V PLA<sub>2</sub> (3G1): sc-18828. Western blot analysis of human recombinant group V PLA<sub>2</sub>.

group V PLA 2 (C-4) - sc-393606 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
group V PLA<sub>2</sub> (C-4): sc-393606. Western blot analysis of group V PLA<sub>2</sub> expression in mouse thymus tissue extract (A) and NIH/3T3 (B), A-10 (C) and HL-60 (D) whole cell lysates.

Anti-Secretory phospholipase A2 Type V antibody - ab118496 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab118496 at 10 &microg/ml staining Secretory phospholipase A2 Type V in Human Skeletal Muscle by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-Secretory phospholipase A2 Type V antibody - ab97847 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Secretory phospholipase A2 Type V antibody (ab97847) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus cell lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Secretory phospholipase A2 Type V antibody - ab97848 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Secretory phospholipase A2 Type V antibody - ab23709 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Secretory phospholipase A2 Type V staining in human heart formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab23709, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Secretory phospholipase A2 Type V antibody [3G1] - ab111959 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G1

Anti-Secretory phospholipase A2 Type V antibody [MCL-3G1] - ab23708 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MCL-3G1
All lanes : Anti-Secretory phospholipase A2 Type V antibody [MCL-3G1] (ab23708) at 1/1000 dilutionLane 2 : sPLA2 (Type II) at 1 µgLane 3 : A10 smooth muscle lysate (iPLA2) at 20 µgLane 4 : Bee venom sPLA2 at 1 µgLane 5 : Semi-pure cPLA2 at 5 µgLane 6 : sPLA2 (Type V) at 0.04 µgLane 7 : sPLA2 (Type V) at 0.008 µgObserved band size : 15 kDa (why is the actual band size different from the predicted?)

Anti-PLA2G5 Antibody (C-Terminus) - LS-C153283 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, AP) - LS-C266461 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, APC) - LS-C266462 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, Biotin) - LS-C266463 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, Azide-free, HRP) - LS-C266465 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, FITC) - LS-C266464 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (aa102-132, PE) - LS-C266466 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (HRP) - LS-C317544 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody - LS-C317545 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody - LS-C318481 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (HRP) - LS-C318482 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (FITC) - LS-C318913 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (Biotin) - LS-C318914 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLA2G5 Antibody (C-Terminus) - LS-C107506 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PLA2G5 antibody LS-C107506 Western blot of Fetal Thymus lysate.
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