Itga2b

Gene Symbol	Itga2b
Entrez Gene	16399
Alt Symbol	AI172977, CD41, CD41B, GpIIb, alphaIIb
Species	Mouse
Gene Type	protein-coding
Description	integrin alpha 2b
Other Description	GP IIb|GPalpha IIb|alpha IIb|integrin alpha-IIb|platelet glycoprotein IIb of IIb/II Ia complex|platelet membrane glycoprotein IIb
Swissprots	Q3U3R7 Q9QUM0 Q9Z2M0 Q64229
Accessions	AAF06996 EDL34136 Q9QUM0 AF045019 AAD02339 AF166384 AAF43997 AF170316 AAD56216 AK048700 BAC33425 AK140749 AK142289 BAE25013 AK154619 BAE32718 AK156872 AK157012 AK158443 AK161727 BC120493 AAI20494 BC137570 AAI37571 BY204133 S43388 AAB23054 NM_010575 NP_034705
Function	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Hypertrophic cardiomyopathy (HCM), Rap1 signaling pathway, PI3K-Akt signaling pathway, Dilated cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Integrin alpha-IIb (Itga2b/CD41), Mouse, ELISA Kit - CSB-E17421m from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Integrin alpha-IIb, Itga2b, Mouse, ELISA Kit - E0614m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Integrin Alpha 2B, ELISA Kit - MBS061005 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin alpha-IIb (Itga2b/CD41) , ELISA Kit - MBS913635 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Mouse Integrin alpha-IIb (Itga2b/CD41) ELISA Kit - CSB-E17421m from Cusabio Category ELISA Kit Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Integrin alpha-IIb, ELISA Kit - MBS288512 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.31 ng/mL -20.0 ng/mL.

Mouse GPIIb/IIIa(Platelet Membrane Glycoprotein IIb/IIIa complex) ELISA Kit - E-EL-M0927 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.23 ng/mL Range 0.39~25 ng/mL

Mouse Integrin alpha-IIb ELISA Kit - abx254778 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Mouse Integrin alpha-IIb (Itga2b/CD41) ELISA Kit - EKC37115 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Mouse Integrin alpha-IIb ELISA Kit - EKE53060 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

Itga2b - EKM0846 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Itga2b - EKM846 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Mouse GPIIb / IIIa ELISA Kit - E054654 from Biobool Category ELISA Kit

Mouse Itga2b ELISA Kit - E056873 from Biobool Category ELISA Kit

ITGA2B ELISA Kit (Mouse) (OKEH03165) - OKEH03165 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity 0.156 ng/mL Range 0.312 - 20 ng/mL

Mouse Integrin alpha-IIb ELISA Kit - EK2036 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 0.312-20 ng/mL

Integrin alpha-IIb, ELISA Kit - MBS9425884 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 0.312-20 ng/mL

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