Smad1

Gene Symbol Smad1
Entrez Gene 17125
Alt Symbol AI528653, Madh1, Madr1, Mlp1, MusMLP
Species Mouse
Gene Type protein-coding
Description SMAD family member 1
Other Description MAD homolog 1|Smad 1|dwarfin-A|dwf-A|mMad1|mad-related protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|mothers-against-DPP-related 1
Swissprots Q9CYK6 P70442 Q6GT95 P70340
Accessions AAG41407 EDL10873 P70340 AK017583 BAB30820 AK034045 BAC28558 AK054104 BAC35658 AK084505 BAC39200 AK087692 BAC39970 AK158509 BC058693 AAH58693 U58992 AAC52785 U74359 AAB18256 XM_006530746 XP_006530809 NM_008539 NP_032565
Function Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). {ECO:0000250, ECO:0000269|PubMed:15329343}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. Colocalizes with LEMD3 at the nucleus inner membrane (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitous.
Top Pathways TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

Mouse-Smad1-Antibody-Center - AP21203c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Smad1 Antibody (Center) at 1:1000 dilution + mouse skeletal muscle lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Smad1 antibody (Ser187) - 70R-33659 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Smad1/5/9 antibody - 70R-31922 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Smad1 antibody - 70R-33660 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Smad1 Antibody - abx104230 from Abbexa

Host Rabbit
Clonality Polyclonal

Anti-SMAD1 - 10-P2114-1 from ARP American Research Products

Host Rabbit
Clonality Polyclonal

Smad1, Polyclonal Antibody - MBS620315 from MyBioSource

Prices $725.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Smad1, Polyclonal Antibody - MBS176187 from MyBioSource

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Smad1, Polyclonal Antibody - MBS621285 from MyBioSource

Prices $725.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Smad1 Antibody PA2114 - PA2114 from Boster Bio

Prices $200.00
Sizes 1
Host Rabbit
Clonality Polyclonal

Smad1 Antibody - middle region (OAAB19163) - OAAB19163 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SMAD1 antibody - 70R-50024 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Smad1, Polyclonal Antibody - MBS9203061 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Smad1/5/9, Polyclonal Antibody - MBS5300829 from MyBioSource

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

anti-Smad1 antibody - ARG51284 from Arigo Biolaboratories

ARG51284 anti-Smad1 antibody WB image Western Blot: extracts from HeLa cells stained with anti-Smad1 antibody ARG51284.
ARG51848 anti-Smad1 phospho (Ser206) antibody WB image Western Blot: extracts from HeLa cells untreated or treated with PMA stained with anti-Smad1 (phospho Ser206) antibody ARG51848.
ARG51794 anti-Smad1 phospho (Ser465) antibody WB image Western Blot: extracts from HeLa cells untreated or treated with PMA stained with anti-Smad1 (phospho Ser465) antibody ARG51794.

Mothers Against Decapentaplegic Homolog 1, Polyclonal Antibody - MBS2027045 from MyBioSource

Prices $150.00, $290.00, $460.00
Sizes 20 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

SMAD1 Antibody (R31227) - R31227 from NSJ Bioreagent

Prices $285.00
Sizes 100 µg (0.5mg/ml if reconstituted with 0.2ml sterile DI water)
Host Rabbit
Clonality Polyclonal
Western blot testing of SMAD1 antibody and Lane 1: SMMC-7721; 2: K562; 3: HT1080; 4: HeLa; 5: Jurkat cell lysate. Predicted molecular weight: 52~60 kDa.

Smad1 Antibody (F53187) - F53187 from NSJ Bioreagent

Prices $125.00, $299.00
Sizes 80 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide), 400 µl (In 1X PBS, pH 7.4, with 0.09% sodium azide)
Host Rabbit
Clonality Polyclonal
Western blot testing of Smad1 antibody at 1:1000 dilution + mouse skeletal muscle lysate; Predicted molecular weight: 52~60 kDa.

Anti-SMAD1 Antibody A00728 - A00728 from Boster Bio

Prices $329.00
Sizes 1
Host Rabbit
Clonality Polyclonal

Mothers Against Decapentaplegic Homolog 1 (Smad1) Polyclonal Antibody - CAU27456 from Biomatik

Prices $103.00, $240.00, $343.00, $550.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Anti-Smad1-Antibody - ABO11421 from Abgent, a WuXi AppTec company

Prices $200.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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