Smad1

Gene Symbol	Smad1
Entrez Gene	17125
Alt Symbol	AI528653, Madh1, Madr1, Mlp1, MusMLP
Species	Mouse
Gene Type	protein-coding
Description	SMAD family member 1
Other Description	MAD homolog 1|Smad 1|dwarfin-A|dwf-A|mMad1|mad-related protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|mothers-against-DPP-related 1
Swissprots	Q9CYK6 P70442 Q6GT95 P70340
Accessions	AAG41407 EDL10873 P70340 AK017583 BAB30820 AK034045 BAC28558 AK054104 BAC35658 AK084505 BAC39200 AK087692 BAC39970 AK158509 BC058693 AAH58693 U58992 AAC52785 U74359 AAB18256 XM_006530746 XP_006530809 NM_008539 NP_032565
Function	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). {ECO:0000250, ECO:0000269|PubMed:15329343}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. Colocalizes with LEMD3 at the nucleus inner membrane (By similarity). {ECO:0000250}.
Tissue Specificity	Ubiquitous.
Top Pathways	TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

ATP Binding Cassette Transporter C6 (ABCC6), Mouse, ELISA Kit - SED626Mu from ARP American Research Products Category ELISA Kit Prices $740.00 Sizes 96 t Sensitivity 0.124ng/mL Range 0.312-20ng/mL

Mothers Against Decapentaplegic Homolog 1, Mouse, ELISA Kit - E03S0269 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25 ng/mL,

Mothers against decapentaplegic homolog 1, Smad1, Mouse, ELISA Kit - E0647m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse Smad1 ELISA Kit - MS0276 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse MADH 1 ELISA Kit - MS0012 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Smad1/MADH1(Mothers Against Decapentaplegic Homolog 1) ELISA Kit - E-EL-M1062 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Mothers Against Decapentaplegic Homolog 1, ELISA Kit - MBS036623 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mothers Against Decapentaplegic Homolog 1, ELISA Kit - MBS725295 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Smad1, ELISA Kit - MBS2506445 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Mouse Mothers Against Decapentaplegic Homolog 1 ELISA - E03S0269 from BlueGene Biotech Category ELISA Kit

ELISA Kit for ATP Binding Cassette Transporter C6 (ABCC6) - SED626Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Mouse Smad1/MADH1(Mothers Against Decapentaplegic Homolog 1) ELISA Kit - E-EL-M1062 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Mouse Mothers Against Decapentaplegic Homolog 1 (Smad1) ELISA Kit - EKU10154 from Biomatik Category ELISA Kit Prices $756.00, $3,326.00, $6,048.00 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

Mouse Smad1 ELISA Kit - E060459 from Biobool Category ELISA Kit

SMAD1 ELISA Kit (Mouse) (OKEH05787) - OKEH05787 from Aviva Systems Biology Category ELISA Kit Prices $440.00 Sizes 96 wells Sensitivity 31.25 pg/mL Range 62.5-4,000 pg/mL

Mouse MADH 1 ELISA Kit - EMS0012 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Smad1 ELISA Kit - EMS0276 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Multidrug resistance-associated protein 6 (ABCC6) ELISA Kit - AE23138MO from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.124 ng/mL Range 0.312-20 ng/mL

Mothers against decapentaplegic homolog 1, ELISA Kit - MBS2886222 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mothers Against Decapentaplegic Homolog 1 (Smad1) , ELISA Kit - MBS2088137 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 0.125ng/mL. Range 0.312-20ng/mL

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