Smad1

Gene Symbol	Smad1
Entrez Gene	17125
Alt Symbol	AI528653, Madh1, Madr1, Mlp1, MusMLP
Species	Mouse
Gene Type	protein-coding
Description	SMAD family member 1
Other Description	MAD homolog 1|Smad 1|dwarfin-A|dwf-A|mMad1|mad-related protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|mothers-against-DPP-related 1
Swissprots	Q9CYK6 P70442 Q6GT95 P70340
Accessions	AAG41407 EDL10873 P70340 AK017583 BAB30820 AK034045 BAC28558 AK054104 BAC35658 AK084505 BAC39200 AK087692 BAC39970 AK158509 BC058693 AAH58693 U58992 AAC52785 U74359 AAB18256 XM_006530746 XP_006530809 NM_008539 NP_032565
Function	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). {ECO:0000250, ECO:0000269|PubMed:15329343}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. Colocalizes with LEMD3 at the nucleus inner membrane (By similarity). {ECO:0000250}.
Tissue Specificity	Ubiquitous.
Top Pathways	TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse Smad1 ORF clone - CDCH083302 from Creative Biomart Species Mouse Accession NM_008539

Mouse Smad1 ORF clone - CDCH083303 from Creative Biomart Species Mouse Accession NM_008539

Mouse Smad1 ORF Clone(NM_008539.3) - CDCL176323 from Creative Biomart Species Mouse Accession NM_008539.3

Mouse Smad1 ORF Clone(NM_008539.3) - CDCR245692 from Creative Biomart Species Mouse Accession NM_008539.3

Mouse Smad1 ORF Clone(NM_008539.3) - CDCR245693 from Creative Biomart Species Mouse Accession NM_008539.3

Mouse Smad1 ORF clone(NM_008539.3) - CDCL186232 from Creative Biomart Species Mouse Accession NM_008539.3

Mouse Smad1 Gene ORF cDNA clone in cloning vector - MG50859-G from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-Flag tag - MG50859-CF from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-Myc tag - MG50859-NM from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-Myc tag - MG50859-CM from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG50859-ACG from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-His tag - MG50859-CH from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-HA tag - MG50859-CY from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-His tag - MG50859-NH from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid - MG50859-UT from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-HA tag - MG50859-NY from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - MG50859-ANG from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-Flag tag - MG50859-NF from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG50859-ACR from Sino Biological Species Mouse

Mouse Smad1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - MG50859-ANR from Sino Biological Species Mouse

Mouse Smad1 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged - MG50859-G-Y from Sino Biological Species Mouse Accession NM_008539.3

Mouse Smad1 ORF clone(NM_008539.3) - CDCL186232 from Creative biogene Species Mouse

Mouse Smad1 ORF Expression Clone, Myc-tagged - orb145313 from Biorbyt Prices $264.00 Sizes 10 μg Species Mouse

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