Smad1

Gene Symbol Smad1
Entrez Gene 17125
Alt Symbol AI528653, Madh1, Madr1, Mlp1, MusMLP
Species Mouse
Gene Type protein-coding
Description SMAD family member 1
Other Description MAD homolog 1|Smad 1|dwarfin-A|dwf-A|mMad1|mad-related protein 1|mothers against DPP homolog 1|mothers against decapentaplegic homolog 1|mothers-against-DPP-related 1
Swissprots Q9CYK6 P70442 Q6GT95 P70340
Accessions AAG41407 EDL10873 P70340 AK017583 BAB30820 AK034045 BAC28558 AK054104 BAC35658 AK084505 BAC39200 AK087692 BAC39970 AK158509 BC058693 AAH58693 U58992 AAC52785 U74359 AAB18256 XM_006530746 XP_006530809 NM_008539 NP_032565
Function Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). {ECO:0000250, ECO:0000269|PubMed:15329343}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. Colocalizes with LEMD3 at the nucleus inner membrane (By similarity). {ECO:0000250}.
Tissue Specificity Ubiquitous.
Top Pathways TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

Mouse Smad1 Protein - abx068066 from Abbexa

Category Protein
Source E.coli
Species Mouse

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant ATP Binding Cassette Transporter C6 (ABCC6) - RPD626Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Mothers against decapentaplegic homolog 1(Smad1) - CSB-YP021786MO CSB-EP021786MO CSB-BP021786MO CSB-MP021786MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Mothers Against Decapentaplegic Homolog 1 (Smad1) - RPU142803 from Biomatik

Category Protein
Prices $236.50, $473.00, $709.50
Sizes 10 µg, 50 µg, 100 µg
Source E.coli
Species Mouse

Recombinant Mouse SMAD1 Protein - SMAD1-15584M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Mouse-Smad1-Blocking-Peptide-Center - BP21203c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
Species Mouse

Recombinant Mothers Against Decapentaplegic Homolog 1 (Smad1) - RPU42803 from Biomatik

Category Protein
Prices $189.00, $387.00, $592.00, $705.20
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Mouse

SMAD1 Recombinant Protein (OPCD07061) - OPCD07061 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Mothers against decapentaplegic homolog 1 (Smad1), Recombinant Protein - MBS960370 from MyBioSource

Category Protein
Prices $1,980.00, $2,440.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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