G6PC

Gene Symbol G6PC
Entrez Gene 2538
Alt Symbol G6PC1, G6PT, GSD1, GSD1a
Species Human
Gene Type protein-coding
Description glucose-6-phosphatase, catalytic subunit
Other Description G-6-Pase|G6Pase|G6Pase-alpha|glucose-6-phosphatase|glucose-6-phosphatase alpha
Swissprots K7EL82 P35575 B4E1C3 A1L4C0
Accessions AAD11621 CAA65638 EAW60901 EAW60902 P35575 AK303771 BAG64735 AK313982 BAG36695 AW614228 BC130478 AAI30479 BC136369 AAI36370 HQ258400 ADR83154 U01120 AAA16222 NM_000151 NP_000142 NM_001270397 NP_001257326
Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Glucagon signaling pathway, AMPK signaling pathway, PI3K-Akt signaling pathway, Carbohydrate digestion and absorption, Glycolysis / Gluconeogenesis

G6Pase-α (H-4) - sc-398155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G6Pase-α (H-4): sc-398155. Western blot analysis of G6Paseα expression in Hep G2 whole cell lysate.

G6Pase-α (C-14) - sc-27198 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G6Pase-α (C-14): sc-27198. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

G6Pase-α (N-19) - sc-27196 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G6Pase-α (N-19): sc-27196. Western blot analysis of human recombinant G6Pase-α fusion protein.

G6Pase-α (H-60) - sc-25840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G6Pase-α (H-60): sc-25840. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-glucose-6-phosphatase, catalytic subunit antibody - ab93857 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-glucose-6-phosphatase, catalytic subunit antibody (ab93857) at 1 µg/mlLane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate with immunising peptide at 1 µg/mlLane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate with immunising peptide at 1 µg/mlLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, FITC) - LS-C214449 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, APC) - LS-C214448 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, AP) - LS-C214446 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, Biotin) - LS-C214450 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, Azide-free, HRP) - LS-C214451 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149, PE) - LS-C214452 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149) - LS-C321504 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-G6PC / Glucose-6-Phosphatase Antibody (N-Terminus) - LS-C135157 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
G6PC antibody LS-C135157 Western blot of Mouse Intestine lysate. Antibody concentration 1 ug/ml.

Anti-G6PC / Glucose-6-Phosphatase Antibody (aa123-149) - LS-C166302 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
G6PC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

G6PC Antibody - NBP1-80533 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: G6PC Antibody [NBP1-80533] - Sample Tissue: Mouse Lung Antibody Dilution: 1.0ug/ml

G6PC Antibody - NBP2-31916 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

G6PC Antibody - NBP1-59361 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: G6PC Antibody [NBP1-59361] - Sample Tissue: Human Fetal Lung, Lane A: Primary Antibody, Lane B: Primary Antibody + Blocking Peptide, Primary Antibody Concentration: 1ug/ml, Peptide Concentration: 5ug/ml, Lysate Quantity: 25ug/lane/lane, Gel Concentration: 0.12

ANTI-G6PC (CENTER) antibody produced in rabbit - SAB1303137 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-G6PC (Center): <B>Cat. No. SAB1303137</B>: Western blot analysis of G6PC Antibody (Center) in K562 cell line lysates (35 μg/lane).

Anti-G6PC antibody produced in rabbit - SAB2100870 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-G6PC: <B>Cat. No. SAB2100870</B>: Immunohistochemistry of G6PC in Human Kidney tissue with G6PC antibody at 4-8 μg/mL.

Anti-G6PC antibody produced in rabbit - HPA052324 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-G6PC: <B>Cat. No. HPA052324</B>: Immunohistochemical staining of Human stomach, upper shows strong cytoplasmic and membranous positivity in glandular cells.

G6PC antibody - N-terminal region (ARP44224_P050) - ARP44224_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

G6PC Antibody - middle region (OAAB02641) - OAAB02641 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

G6PC-Antibody-Center - AP5224c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of G6PC Antibody (Center) (Cat. #AP5224c) in K562 cell line lysates (35ug/lane).G6PC (arrow) was detected using the purified Pab.

G6PC antibody, N-term - GTX46748 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-G6PC antibody, N-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX46748

G6PC antibody - 70R-6258 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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