Central carbon metabolism in cancer



AKT1 - from Human

Gene Symbol AKT1
Entrez Gene 207
Alt Symbol AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Gene Type protein-coding
Description v-akt murine thymoma viral oncogene homolog 1

AKT2 - from Human

Gene Symbol AKT2
Entrez Gene 208
Alt Symbol HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
Gene Type protein-coding
Description v-akt murine thymoma viral oncogene homolog 2

EGFR - from Human

Gene Symbol EGFR
Entrez Gene 1956
Alt Symbol ERBB, ERBB1, HER1, NISBD2, PIG61, mENA
Gene Type protein-coding
Description epidermal growth factor receptor

ERBB2 - from Human

Gene Symbol ERBB2
Entrez Gene 2064
Alt Symbol CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Gene Type protein-coding
Description erb-b2 receptor tyrosine kinase 2

FGFR1 - from Human

Gene Symbol FGFR1
Entrez Gene 2260
Alt Symbol BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1
Gene Type protein-coding
Description fibroblast growth factor receptor 1

FGFR3 - from Human

Gene Symbol FGFR3
Entrez Gene 2261
Alt Symbol ACH, CD333, CEK2, HSFGFR3EX, JTK4
Gene Type protein-coding
Description fibroblast growth factor receptor 3

FGFR2 - from Human

Gene Symbol FGFR2
Entrez Gene 2263
Alt Symbol BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Gene Type protein-coding
Description fibroblast growth factor receptor 2

FLT3 - from Human

Gene Symbol FLT3
Entrez Gene 2322
Alt Symbol CD135, FLK-2, FLK2, STK1
Gene Type protein-coding
Description fms-related tyrosine kinase 3

MTOR - from Human

Gene Symbol MTOR
Entrez Gene 2475
Alt Symbol FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gene Type protein-coding
Description mechanistic target of rapamycin (serine/threonine kinase)

G6PD - from Human

Gene Symbol G6PD
Entrez Gene 2539
Alt Symbol G6PD1
Gene Type protein-coding
Description glucose-6-phosphate dehydrogenase

GCK - from Human

Gene Symbol GCK
Entrez Gene 2645
Alt Symbol FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2
Gene Type protein-coding
Description glucokinase (hexokinase 4)

GLS - from Human

Gene Symbol GLS
Entrez Gene 2744
Alt Symbol AAD20, GAC, GAM, GLS1, KGA
Gene Type protein-coding
Description glutaminase

HIF1A - from Human

Gene Symbol HIF1A
Entrez Gene 3091
Alt Symbol HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
Gene Type protein-coding
Description hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

HK1 - from Human

Gene Symbol HK1
Entrez Gene 3098
Alt Symbol HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1
Gene Type protein-coding
Description hexokinase 1

HK2 - from Human

Gene Symbol HK2
Entrez Gene 3099
Alt Symbol HKII, HXK2
Gene Type protein-coding
Description hexokinase 2

HK3 - from Human

Gene Symbol HK3
Entrez Gene 3101
Alt Symbol HKIII, HXK3
Gene Type protein-coding
Description hexokinase 3 (white cell)

HRAS - from Human

Gene Symbol HRAS
Entrez Gene 3265
Alt Symbol C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras
Gene Type protein-coding
Description Harvey rat sarcoma viral oncogene homolog

IDH1 - from Human

Gene Symbol IDH1
Entrez Gene 3417
Alt Symbol HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD
Gene Type protein-coding
Description isocitrate dehydrogenase 1 (NADP+), soluble

KIT - from Human

Gene Symbol KIT
Entrez Gene 3815
Alt Symbol C-Kit, CD117, PBT, SCFR
Gene Type protein-coding
Description v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

KRAS - from Human

Gene Symbol KRAS
Entrez Gene 3845
Alt Symbol C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Gene Type protein-coding
Description Kirsten rat sarcoma viral oncogene homolog

LDHA - from Human

Gene Symbol LDHA
Entrez Gene 3939
Alt Symbol GSD11, HEL-S-133P, LDH1, LDHM, PIG19
Gene Type protein-coding
Description lactate dehydrogenase A

MET - from Human

Gene Symbol MET
Entrez Gene 4233
Alt Symbol AUTS9, HGFR, RCCP2, c-Met
Gene Type protein-coding
Description MET proto-oncogene, receptor tyrosine kinase

MYC - from Human

Gene Symbol MYC
Entrez Gene 4609
Alt Symbol MRTL, MYCC, bHLHe39, c-Myc
Gene Type protein-coding
Description v-myc avian myelocytomatosis viral oncogene homolog

NRAS - from Human

Gene Symbol NRAS
Entrez Gene 4893
Alt Symbol ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
Gene Type protein-coding
Description neuroblastoma RAS viral (v-ras) oncogene homolog

NTRK1 - from Human

Gene Symbol NTRK1
Entrez Gene 4914
Alt Symbol MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
Gene Type protein-coding
Description neurotrophic tyrosine kinase, receptor, type 1
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